Manuscript: Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell.

Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell.

  • John J Tyson
  • Katherine C Chen
  • Bela Novak
Curr. Opin. Cell Biol. 2003; 15 (2): 221-231
Abstract
The physiological responses of cells to external and internal stimuli are governed by genes and proteins interacting in complex networks whose dynamical properties are impossible to understand by intuitive reasoning alone. Recent advances by theoretical biologists have demonstrated that molecular regulatory networks can be accurately modeled in mathematical terms. These models shed light on the design principles of biological control systems and make predictions that have been verified experimentally.
Model Organism Tissue Process type
tyson10 Homo sapiens signal transduction
tyson11 Homo sapiens signal transduction
tyson12 Homo sapiens signal transduction
tyson13 Homo sapiens signal transduction
tyson14 Homo sapiens signal transduction
tyson8 Homo sapiens signal transduction
tyson9 Homo sapiens signal transduction