#yugi1



#reactions
re1:
 $pool = {1.0}s4
  s9 / (K_PFKL_f26bp + s9) * (K_PFKL_akg / (K_PFKL_akg + s7)) * (K_PFKL_pep / (K_PFKL_pep + s5)) * (K_PFKL_cit / (K_PFKL_cit + s10)) * (K_PFKL_icit / (K_PFKL_icit + s6)) * (K_PFKL_mal / (K_PFKL_mal + s8)) * (s13 / (K_PFKL_PHOS_S775 + s13)) * (Vf_PFKL * s22 / (K_PFKL_f6p + s22))
re10:
 {1.0}s13 = {1.0}s20
  -k_pfkl_s775
re11:
 {1.0}s3 = {1.0}s21
  -k_f6p
re2:
 {1.0}s4 = $pool
  K_FBPase_f26bp / (K_FBPase_f26bp + s9) * (s10 / (K_FBPase_cit + s10)) * (Vf_FBPase * s4 / (K_FBPase_f16bp + s4))
re3:
 {1.0}s4 = {1.0}s11
  k_ALDO * s4
re4:
 {1.0}s8 = {1.0}s14
  -k_mal
re5:
 {1.0}s7 = {1.0}s15
  -k_akg
re6:
 {1.0}s5 = {1.0}s16
  -k_pep
re7:
 {1.0}s6 = {1.0}s17
  -k_icit
re8:
 {1.0}s9 = {1.0}s18
  -k_f26bp
re9:
 {1.0}s10 = {1.0}s19
  -k_cit


#parameters
K_FBPase_cit = 0.0211646
K_FBPase_f16bp = 0.104089638
K_FBPase_f26bp = 17.51744342
K_PFKL_PHOS_S775 = 6.283705757
K_PFKL_akg = 24661.01154
K_PFKL_cit = 41.30426029
K_PFKL_f26bp = 1.282443082
K_PFKL_f6p = 0.014114844
K_PFKL_icit = 1784.508205
K_PFKL_mal = 9.544729149
K_PFKL_pep = 0.633518366
Vf_FBPase = 9.932861302
Vf_PFKL = 695063.7194
k_ALDO = 0.008187906
k_akg = -3.544494721
k_cit = -0.351935646
k_f26bp = -0.083430336
k_f6p = -0.930115636
k_icit = -0.038210156
k_mal = 1.005530417
k_pep = 43.99195576
k_pfkl_s775 = -0.011384308
default = 1.0


#initial values
s1 = 1.0
s10 = 17.7476118652
s11 = 0.0
s12 = 1.0
s13 = 0.768939345
s14 = 0.0
s15 = 0.0
s16 = 0.0
s17 = 0.0
s18 = 0.0
s19 = 0.0
s2 = 1.0
s20 = 0.0
s21 = 0.0
s3 = 14.0774258421
s4 = 104.07239819
s5 = 108.094519859
s6 = 1.79487179487
s7 = 25.1885369533
s8 = 68.8788335846
s9 = 1.0


#assignment rules
!F s22 = s3