begin name
yugi1
end name

begin reactions
re1 {1.0}$EXTERNAL = {1.0}s4
re10 {1.0}s13 = {1.0}s20
re11 {1.0}s3 = {1.0}s21
re2 {1.0}s4 = {1.0}$EXTERNAL
re3 {1.0}s4 = {1.0}s11
re4 {1.0}s8 = {1.0}s14
re5 {1.0}s7 = {1.0}s15
re6 {1.0}s5 = {1.0}s16
re7 {1.0}s6 = {1.0}s17
re8 {1.0}s9 = {1.0}s18
re9 {1.0}s10 = {1.0}s19
end reactions

begin rate equations
re1 = (KPFKLakg*KPFKLcit*KPFKLicit*KPFKLmal*KPFKLpep*s22*VfPFKL*s13[t]*s9[t])/((KPFKLf6p + s22)*(KPFKLcit + s10[t])*(KPFKLPHOSS775 + s13[t])*(KPFKLpep + s5[t])*(KPFKLicit + s6[t])*(KPFKLakg + s7[t])*(KPFKLmal + s8[t])*(KPFKLf26bp + s9[t]))
re10 = -kpfkls775
re11 = -kf6p
re2 = (KFBPasef26bp*VfFBPase*s10[t]*s4[t])/((KFBPasecit + s10[t])*(KFBPasef16bp + s4[t])*(KFBPasef26bp + s9[t]))
re3 = kALDO*s4[t]
re4 = -kmal
re5 = -kakg
re6 = -kpep
re7 = -kicit
re8 = -kf26bp
re9 = -kcit
end rate equations

begin parameters
KFBPasecit = 0.0211646
KFBPasef16bp = 0.104089638
KFBPasef26bp = 17.51744342
KPFKLPHOSS775 = 6.283705757
KPFKLakg = 24661.01154
KPFKLcit = 41.30426029
KPFKLf26bp = 1.282443082
KPFKLf6p = 0.014114844
KPFKLicit = 1784.508205
KPFKLmal = 9.544729149
KPFKLpep = 0.633518366
VfFBPase = 9.932861302
VfPFKL = 695063.7194
kALDO = 0.008187906
kakg = -3.544494721
kcit = -0.351935646
kf26bp = -0.083430336
kf6p = -0.930115636
kicit = -0.038210156
kmal = 1.005530417
kpep = 43.99195576
kpfkls775 = -0.011384308
default = 1.0
end parameters

begin initial conditions
s1[0] = s1i
s10[0] = s10i
s11[0] = s11i
s12[0] = s12i
s13[0] = s13i
s14[0] = s14i
s15[0] = s15i
s16[0] = s16i
s17[0] = s17i
s18[0] = s18i
s19[0] = s19i
s2[0] = s2i
s20[0] = s20i
s21[0] = s21i
s3[0] = s3i
s4[0] = s4i
s5[0] = s5i
s6[0] = s6i
s7[0] = s7i
s8[0] = s8i
s9[0] = s9i
end initial conditions

begin initial values
s1i = 1.0
s10i = 17.7476118652
s11i = 0.0
s12i = 1.0
s13i = 0.768939345
s14i = 0.0
s15i = 0.0
s16i = 0.0
s17i = 0.0
s18i = 0.0
s19i = 0.0
s2i = 1.0
s20i = 0.0
s21i = 0.0
s3i = 14.0774258421
s4i = 104.07239819
s5i = 108.094519859
s6i = 1.79487179487
s7i = 25.1885369533
s8i = 68.8788335846
s9i = 1.0
end initial values

begin assignment rules
s22 := s3[t]
end assignment rules

begin function definitions
end function definitions

begin events
ev30min = (t > 30, {kcit -> 0.306686777, kf6p -> 0.070387129, kicit -> 0.031674208, kf26bp -> -0.003055632, kmal -> 0.502765209, kpep -> -0.301659125, kpfkls775 -> 0.006730598, kakg -> 0.369532428}, 0)
ev20min = (t > 20, {kpep -> -3.619909502, kpfkls775 -> 0.006730598, kmal -> 1.206636501, kakg -> 0.226244344, kcit -> 0.377073906, kf6p -> -0.165912519, kicit -> 0.031674208, kf26bp -> -0.032601514}, 0)
ev15min = (t > 15, {kakg -> 1.085972851, kcit -> 0.452488688, kf6p -> -0.12066365, kicit -> -0.018099548, kf26bp -> 0.100115778, kmal -> 1.809954751, kpfkls775 -> 0.006730598, kpep -> -4.826546003}, 0)
ev10min = (t > 10, {kakg -> 0.36199095, kcit -> 1.085972851, kf6p -> -1.055806938, kicit -> -0.038210156, kmal -> 3.921568627, kpep -> 9.049773756, kpfkls775 -> 0.006730598, kf26bp -> -0.050207413}, 0)
ev5min = (t > 5, {kakg -> 0, kcit -> -0.211161388, kf6p -> 0.271493213, kf26bp -> 0.119075279, kmal -> -0.904977376, kpep -> -6.334841629, kpfkls775 -> 0.057596439, kicit -> -0.038210156}, 0)
ev2min = (t > 2, {kakg -> -1.357466063, kf6p -> 1.357466063, kicit -> -0.038210156, kf26bp -> 0.028924455, kmal -> -1.508295626, kpep -> 7.54147813, kpfkls775 -> -0.011384308, kcit -> 0.351935646}, 0)
ev45min = (t > 45, {kakg -> 0.369532428, kcit -> 0.306686777, kicit -> 0.031674208, kf26bp -> -0.003055632, kmal -> 0.502765209, kpep -> -0.301659125, kpfkls775 -> 0.00673059831429, kf6p -> 0.070387129}, 0)
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units