#wortel4



#reactions
v_1:
 $pool = {1.0}a
  (aext*e1*kcat1)/(kmaext1*(1 + aext/kmaext1 + a/kma1))
v_10:
 {1.0}g = {1.0}d
  (e10*kcat10*g)/(kmg10*(1 + d/kmd10 + g/kmg10))
v_11:
 {1.0}fm + {1.0}p = $pool
  (e11*kcat11*fm*p)/(kmfm11*kmp11*(1 + (ftot - fm)/kmfp11 + fm/kmfm11)*(1 + pext/kmpext11 + p/kmp11))
v_2:
 $pool = {1.0}b + {1.0}fm
  (bext*e2*kcat2*a*(ftot - fm)*(1 - (b*fm)/(bext*keq2*(ftot - fm))))/(kaa2*kmbext2*kmfp2*(1 + a/kaa2)*(1 + bext/kmbext2 + b/kmb2)*(1 + (ftot - fm)/kmfp2 + fm/kmfm2))
v_3:
 {1.0}a = {1.0}b
  (e3*kcat3*a)/(kma3*(1 + a/kma3 + b/kmb3))
v_4:
 {1.0}a = {1.0}c
  (e4*kcat4*a*(1 - c/(keq4*a)))/(kma4*(1 + a/kma4 + c/kmc4))
v_5:
 {1.0}a = {1.0}d
  (e5*kcat5*a*c)/(kac5*kma5*(1 + c/kac5)*(1 + a/kma5 + d/kmd5))
v_6:
 {1.0}b = {1.0}c
  (e6*kcat6*b*(1 - c/(keq6*b)))/(kmb6*(1 + b/kmb6 + c/kmc6))
v_7:
 {1.0}b = {1.0}p
  (e7*kcat7*b)/(kmb7*(1 + c/kic7)*(1 + b/kmb7 + p/kmp7))
v_8:
 {1.0}c + {1.0}d = {1.0}fm + {1.0}p
  (e8*kcat8*c*d*(ftot - fm))/(kmc8*kmd8*kmfp8*(1 + d/kmd8)*(1 + (ftot - fm)/kmfp8 + fm/kmfm8)*(1 + c/kmc8 + p/kmp8))
v_9:
 {1.0}d = {1.0}g
  (e9*kcat9*d)/(kmd9*(1 + d/kmd9 + g/kmg9))


#parameters
EXTERNAL = 1.0
aext = 2.32175122459047
bext = 1.82097585950486
e1 = 1.97972425219533
e10 = 1e-06
e11 = 0.548430069295763
e2 = 1e-06
e3 = 1e-06
e4 = 1.8765818035848
e5 = 0.154469876349102
e6 = 1e-06
e7 = 1e-06
e8 = 12.9070774037041
e9 = 1e-06
ftot = 5.0
kaa2 = 0.537724121637483
kac5 = 0.45109181910517
kcat1 = 4.35128295344753
kcat10 = 2.04583181726299
kcat11 = 15.6308547611266
kcat2 = 2.08470697013596
kcat3 = 0.659201960419019
kcat4 = 1.21740513898481
kcat5 = 7.48882370581632
kcat6 = 0.26424160469917
kcat7 = 0.515186023045187
kcat8 = 0.148031799420018
kcat9 = 4.00713635555074
keq2 = 2.0
keq4 = 2.0
keq6 = 2.0
kic7 = 1.01557360659626
kma1 = 2.65103841264887
kma3 = 0.183420075929795
kma4 = 6.89306707926306
kma5 = 0.329345484841003
kmaext1 = 0.232175122459047
kmb2 = 0.190218968479388
kmb3 = 0.965624239632328
kmb6 = 0.890368839214066
kmb7 = 5.5364593839414
kmbext2 = 18.2097585950486
kmc4 = 6.56779619616803
kmc6 = 55.7611490930134
kmc8 = 4.70771101695726
kmd10 = 0.417200201130384
kmd5 = 33.0655370631572
kmd8 = 1.79688793384447
kmd9 = 0.104280856663846
kmfm11 = 0.140510704125535
kmfm2 = 8.42083191123236
kmfm8 = 0.660727064408495
kmfp11 = 7.26391447299304
kmfp2 = 1.27736476875397
kmfp8 = 3.23838653900196
kmg10 = 1.38293464784513
kmg9 = 0.43294178975732
kmp11 = 0.571956386391092
kmp7 = 11.3398543717022
kmp8 = 6.64006979927262
kmpext11 = 1.32831286086816
pext = 0.132831286086816
default_compartment = 1.0


#initial values
a = 43.6059113414968
b = 1.0
c = 39.152640553106
d = 875.728067679313
fm = 0.0627769167303887
g = 1.0
p = 1.071877291459


#assignment rules