begin name
wortel4
end name

begin reactions
v1 {1.0}$EXTERNAL = {1.0}a
v10 {1.0}g = {1.0}d
v11 {1.0}fm + {1.0}p = {1.0}$EXTERNAL
v2 {1.0}$EXTERNAL = {1.0}b + {1.0}fm
v3 {1.0}a = {1.0}b
v4 {1.0}a = {1.0}c
v5 {1.0}a = {1.0}d
v6 {1.0}b = {1.0}c
v7 {1.0}b = {1.0}p
v8 {1.0}c + {1.0}d = {1.0}fm + {1.0}p
v9 {1.0}d = {1.0}g
end reactions

begin rate equations
v1 = (aext*e1*kcat1)/(kmaext1*(1 + aext/kmaext1 + a[t]/kma1))
v10 = (e10*kcat10*g[t])/(kmg10*(1 + d[t]/kmd10 + g[t]/kmg10))
v11 = (e11*kcat11*fm[t]*p[t])/(kmfm11*kmp11*(1 + (ftot - fm[t])/kmfp11 + fm[t]/kmfm11)*(1 + pext/kmpext11 + p[t]/kmp11))
v2 = (bext*e2*kcat2*a[t]*(ftot - fm[t])*(1 - (b[t]*fm[t])/(bext*keq2*(ftot - fm[t]))))/(kaa2*kmbext2*kmfp2*(1 + a[t]/kaa2)*(1 + bext/kmbext2 + b[t]/kmb2)*(1 + (ftot - fm[t])/kmfp2 + fm[t]/kmfm2))
v3 = (e3*kcat3*a[t])/(kma3*(1 + a[t]/kma3 + b[t]/kmb3))
v4 = (e4*kcat4*a[t]*(1 - c[t]/(keq4*a[t])))/(kma4*(1 + a[t]/kma4 + c[t]/kmc4))
v5 = (e5*kcat5*a[t]*c[t])/(kac5*kma5*(1 + c[t]/kac5)*(1 + a[t]/kma5 + d[t]/kmd5))
v6 = (e6*kcat6*b[t]*(1 - c[t]/(keq6*b[t])))/(kmb6*(1 + b[t]/kmb6 + c[t]/kmc6))
v7 = (e7*kcat7*b[t])/(kmb7*(1 + c[t]/kic7)*(1 + b[t]/kmb7 + p[t]/kmp7))
v8 = (e8*kcat8*c[t]*d[t]*(ftot - fm[t]))/(kmc8*kmd8*kmfp8*(1 + d[t]/kmd8)*(1 + (ftot - fm[t])/kmfp8 + fm[t]/kmfm8)*(1 + c[t]/kmc8 + p[t]/kmp8))
v9 = (e9*kcat9*d[t])/(kmd9*(1 + d[t]/kmd9 + g[t]/kmg9))
end rate equations

begin parameters
EXTERNAL = 1.0
aext = 2.32175122459047
bext = 1.82097585950486
e1 = 1.97972425219533
e10 = "1e-06"
e11 = 0.548430069295763
e2 = "1e-06"
e3 = "1e-06"
e4 = 1.8765818035848
e5 = 0.154469876349102
e6 = "1e-06"
e7 = "1e-06"
e8 = 12.9070774037041
e9 = "1e-06"
ftot = 5.0
kaa2 = 0.537724121637483
kac5 = 0.45109181910517
kcat1 = 4.35128295344753
kcat10 = 2.04583181726299
kcat11 = 15.6308547611266
kcat2 = 2.08470697013596
kcat3 = 0.659201960419019
kcat4 = 1.21740513898481
kcat5 = 7.48882370581632
kcat6 = 0.26424160469917
kcat7 = 0.515186023045187
kcat8 = 0.148031799420018
kcat9 = 4.00713635555074
keq2 = 2.0
keq4 = 2.0
keq6 = 2.0
kic7 = 1.01557360659626
kma1 = 2.65103841264887
kma3 = 0.183420075929795
kma4 = 6.89306707926306
kma5 = 0.329345484841003
kmaext1 = 0.232175122459047
kmb2 = 0.190218968479388
kmb3 = 0.965624239632328
kmb6 = 0.890368839214066
kmb7 = 5.5364593839414
kmbext2 = 18.2097585950486
kmc4 = 6.56779619616803
kmc6 = 55.7611490930134
kmc8 = 4.70771101695726
kmd10 = 0.417200201130384
kmd5 = 33.0655370631572
kmd8 = 1.79688793384447
kmd9 = 0.104280856663846
kmfm11 = 0.140510704125535
kmfm2 = 8.42083191123236
kmfm8 = 0.660727064408495
kmfp11 = 7.26391447299304
kmfp2 = 1.27736476875397
kmfp8 = 3.23838653900196
kmg10 = 1.38293464784513
kmg9 = 0.43294178975732
kmp11 = 0.571956386391092
kmp7 = 11.3398543717022
kmp8 = 6.64006979927262
kmpext11 = 1.32831286086816
pext = 0.132831286086816
defaultcompartment = 1.0
end parameters

begin initial conditions
a[0] = ai
b[0] = bi
c[0] = ci
d[0] = di
fm[0] = fmi
g[0] = gi
p[0] = pi
end initial conditions

begin initial values
ai = 43.6059113414968
bi = 1.0
ci = 39.152640553106
di = 875.728067679313
fmi = 0.0627769167303887
gi = 1.0
pi = 1.071877291459
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units