#wegner1



#reactions
_103:
 {1.0}_101 + {1.0}_99 = {1.0}_105
  _1 * (k1 * _101 * _99 - k2 * _105)
_125:
 {1.0}_99 = {1.0}_129
  _1 * function_3(k, _96, _99, km)
_132:
 {1.0}_105 = {1.0}_129 + {1.0}_101
  _1 * function_3(k, _96, _105, km)
_139:
 {1.0}_129 = {1.0}_19
  k1 * _129
_149:
 {1.0}_147 + {2.0}_129 = {1.0}_153
  _1 * k1 * _147 * pow(_129, 2)
_156:
 {1.0}_147 = {1.0}_5
  k1 * _147 - k2 * _5
_164:
 {1.0}_153 = {1.0}_9
  k1 * _153
_172:
 {1.0}_25 = {1.0}_174
  k1 * _25 - k2 * _174
_178:
 {1.0}_27 = {1.0}_181
  k1 * _27 - k2 * _181
_192:
 {1.0}_181 + {1.0}_96 = $pool
  _1 * k1 * _181 * _96
_194:
 {1.0}_174 + {1.0}_96 = {1.0}_198
  _1 * (k1 * _174 * _96 - k2 * _198)
_29:
 {1.0}species_27 = {1.0}_5 + {2.0}species_17
  _3 * k1 * species_27
_31:
 {1.0}_9 = {1.0}species_19
  _3 * function_1(_9, Km, V)
_33:
 {1.0}_9 + {2.0}_11 = {1.0}_13
  _3 * (k1 * _9 * pow(_11, 2) - k2 * _13)
_35:
 {3.0}_15 + {1.0}species_13 = {3.0}_19
  k1 * pow(_15, 3) * species_13
_37:
 {1.0}_5 + {2.0}_19 = {1.0}_9
  _3 * k1 * _5 * pow(_19, 2)
_39:
 {1.0}_19 = {1.0}_21
  _3 * function_1(_19, Km, V)
_41:
 {1.0}_21 + {1.0}_15 = $pool
  _3 * k1 * _21 * _15
_43:
 {1.0}_15 + {1.0}_25 = {1.0}_27
  _3 * (k1 * _15 * _25 - k2 * _27)
_77:
 {2.0}_75 = {1.0}_79
  _1 * function_2(parameter_1, k, _75, _75)
_86:
 {1.0}_79 + {2.0}_84 = {1.0}_96
  _1 * (k1 * _79 * pow(_84, 2) - k2 * _96)
reaction_1:
 $pool = {1.0}_75
  _1 * function_4(v)
reaction_10:
 {1.0}_84 = $pool
  _1 * k1 * _84
reaction_11:
 {1.0}_75 = $pool
  _1 * k1 * _75
reaction_12:
 {1.0}_79 = {2.0}_75
  _1 * k1 * _79
reaction_13:
 $pool = {1.0}_99
  _1 * function_4(v)
reaction_14:
 $pool = {1.0}_147
  _1 * function_4(v)
reaction_15:
 {1.0}_147 = $pool
  _1 * k1 * _147
reaction_16:
 {1.0}_101 = $pool
  _1 * k1 * _101
reaction_17:
 {1.0}_129 = {1.0}_99
  _1 * function_1(_129, Km, V)
reaction_18:
 {1.0}species_2 = $pool
  _1 * k1 * species_2
reaction_19:
 {1.0}_15 = {1.0}species_1
  k1 * _15 - k2 * species_1
reaction_2:
 $pool = {1.0}_101
  _1 * function_5(k, k1, species_30)
reaction_20:
 {1.0}_99 = $pool
  _1 * k1 * _99
reaction_21:
 {1.0}species_2 = {1.0}_11
  k1 * species_2 - k2 * _11
reaction_22:
 $pool = {1.0}species_3
  _1 * function_4(v)
reaction_23:
 {1.0}species_3 = $pool
  _1 * k1 * species_3
reaction_24:
 {1.0}species_4 = {1.0}species_3
  _1 * function_1(species_4, Km, V)
reaction_25:
 {1.0}species_18 = {1.0}species_27
  _3 * function_1(species_18, Km, V)
reaction_26:
 {1.0}species_20 = {1.0}species_17
  _3 * function_1(species_20, Km, V)
reaction_27:
 {1.0}species_3 = {1.0}species_4
  _1 * function_3(k, _96, species_3, km)
reaction_28:
 {1.0}species_5 = {1.0}species_4 + {1.0}_101
  _1 * function_3(k, _96, species_5, km)
reaction_29:
 {1.0}species_17 = $pool
  _3 * k1 * species_17
reaction_3:
 $pool = {1.0}_174
  _1 * function_6(k, k1, species_30, species_16, species_23)
reaction_30:
 {1.0}species_3 = {1.0}species_17
  k1 * species_3 - k2 * species_17
reaction_31:
 {1.0}_101 + {1.0}species_3 = {1.0}species_5
  _1 * (k1 * _101 * species_3 - k2 * species_5)
reaction_32:
 {1.0}species_19 = {1.0}_5 + {2.0}_21
  _3 * k1 * species_19
reaction_33:
 {1.0}species_4 = {1.0}species_20
  k1 * species_4
reaction_34:
 {1.0}_147 + {2.0}species_4 = {1.0}species_6
  _1 * k1 * _147 * pow(species_4, 2)
reaction_35:
 {1.0}_5 + {2.0}species_20 = {1.0}species_18
  _3 * k1 * _5 * pow(species_20, 2)
reaction_36:
 {1.0}species_18 + {2.0}_11 = {1.0}species_21
  _3 * (k1 * species_18 * pow(_11, 2) - k2 * species_21)
reaction_37:
 {1.0}species_6 = {1.0}species_18
  k1 * species_6
reaction_38:
 {1.0}species_14 = {1.0}species_20
  k1 * species_14
reaction_39:
 {1.0}_174 = $pool
  _1 * function_7(k1, _174, species_15)
reaction_4:
 $pool = {1.0}species_1
  _1 * function_5(k, k1, species_30)
reaction_40:
 {1.0}species_7 = $pool
  _1 * k1 * species_7
reaction_41:
 {1.0}species_7 = {1.0}species_22
  k1 * species_7 - k2 * species_22
reaction_42:
 $pool = {1.0}species_7
  _1 * function_5(k, k1, species_30)
reaction_43:
 {1.0}species_1 = $pool
  _1 * function_7(k1, species_1, _174)
reaction_44:
 {1.0}_5 + {1.0}species_22 = {1.0}species_23
  _3 * (k1 * _5 * species_22 - k2 * species_23)
reaction_45:
 {1.0}species_3 + {1.0}species_7 = {1.0}species_8
  _1 * (k1 * species_3 * species_7 - k2 * species_8)
reaction_46:
 {1.0}species_24 + {1.0}_25 = {1.0}species_25
  _3 * (k1 * species_24 * _25 - k2 * species_25)
reaction_47:
 $pool = {1.0}species_9
  _1 * function_5(k, k1, species_30)
reaction_48:
 {1.0}species_18 + {2.0}species_22 = {1.0}species_26
  _3 * (k1 * species_18 * pow(species_22, 2) - k2 * species_26)
reaction_49:
 {1.0}species_10 + {1.0}_96 = $pool
  _1 * k1 * species_10 * _96
reaction_5:
 $pool = {1.0}species_2
  _1 * function_5(k, k1, species_30)
reaction_50:
 {1.0}species_25 = {1.0}species_10
  k1 * species_25 - k2 * species_10
reaction_51:
 {1.0}species_9 = $pool
  _1 * function_7(k1, species_9, _174)
reaction_52:
 {1.0}species_24 = {1.0}species_9
  k1 * species_24 - k2 * species_9
reaction_53:
 {1.0}species_18 + {1.0}species_28 = {1.0}species_30
  _3 * (k1 * species_18 * species_28 - k2 * species_30)
reaction_54:
 {1.0}_9 + {1.0}species_28 = {1.0}species_30
  _3 * (k1 * _9 * species_28 - k2 * species_30)
reaction_55:
 {1.0}species_21 + {1.0}species_28 = {1.0}species_29
  _3 * (k1 * species_21 * species_28 - k2 * species_29)
reaction_56:
 {1.0}_13 + {1.0}species_28 = {1.0}species_29
  _3 * (k1 * _13 * species_28 - k2 * species_29)
reaction_57:
 {1.0}species_26 + {1.0}species_28 = {1.0}species_29
  _3 * (k1 * species_26 * species_28 - k2 * species_29)
reaction_58:
 {1.0}_9 + {2.0}species_22 = {1.0}species_11
  k1 * _9 * pow(species_22, 2) - k2 * species_11
reaction_59:
 {1.0}species_11 + {1.0}species_28 = {1.0}species_29
  k1 * species_11 * species_28 - k2 * species_29
reaction_6:
 $pool = {1.0}_84
  _1 * function_4(v)
reaction_60:
 {1.0}species_23 + {1.0}species_28 = {1.0}species_29
  _3 * (k1 * species_23 * species_28 - k2 * species_29)
reaction_61:
 {1.0}_99 + {1.0}species_7 = {1.0}species_12
  _1 * (k1 * _99 * species_7 - k2 * species_12)
reaction_62:
 {3.0}_19 + {3.0}_11 = {1.0}species_13
  k1 * pow(_19, 3) * pow(_11, 3) - k2 * species_13
reaction_63:
 {3.0}species_20 + {3.0}_11 = {1.0}species_14
  k1 * pow(species_20, 3) * pow(_11, 3) - k2 * species_14
reaction_64:
 {1.0}_9 = $pool
  _3 * k1 * _9
reaction_65:
 {1.0}species_18 = $pool
  _3 * k1 * species_18
reaction_66:
 $pool = {1.0}species_15
  _1 * function_4(v)
reaction_67:
 {1.0}species_15 = $pool
  _1 * k1 * species_15
reaction_68:
 {1.0}species_13 + {3.0}species_31 = {3.0}_19
  k1 * species_13 * pow(species_31, 3)
reaction_69:
 {1.0}species_14 + {3.0}species_31 = {1.0}species_20
  k1 * species_14 * pow(species_31, 3)
reaction_7:
 {1.0}_5 + {1.0}_11 = {1.0}species_16
  _3 * (k1 * _5 * _11 - k2 * species_16)
reaction_70:
 {1.0}species_15 = {1.0}species_31
  k1 * species_15 - k2 * species_31
reaction_8:
 {1.0}_99 = {1.0}_21
  k1 * _99 - k2 * _21
reaction_9:
 {1.0}_96 = $pool
  _1 * k1 * _96


#parameters
parameter_1 = 0.01
reaction_31_k1 = 1.0
reaction_31_k2 = 0.1
reaction_32_k1 = 0.0492
reaction_33_k1 = 16.6
reaction_34_k1 = 1000.0
reaction_35_k1 = 255.068
reaction_36_k1 = 1.6
reaction_36_k2 = 1.6
reaction_37_k1 = 0.16
reaction_38_k1 = 0.232
reaction_39_k1 = 0.1
reaction_40_k1 = 0.232
reaction_41_k1 = 0.1
reaction_41_k2 = 0.2
reaction_42_k = 2e-05
reaction_42_k1 = 0.00055
reaction_43_k1 = 0.05
reaction_44_k1 = 1.0
reaction_44_k2 = 0.05288
reaction_45_k1 = 0.1
reaction_45_k2 = 0.1
reaction_46_k1 = 2.9
reaction_46_k2 = 0.2
reaction_47_k = 0.0001
reaction_47_k1 = 0.0022
reaction_48_k1 = 1.6
reaction_48_k2 = 1.6
reaction_49_k1 = 1900.0
reaction_50_k1 = 1.0
reaction_50_k2 = 0.01
reaction_51_k1 = 0.5
reaction_52_k1 = 0.05
reaction_52_k2 = 3.0
reaction_53_k1 = 0.463
reaction_53_k2 = 0.102
reaction_54_k1 = 0.463
reaction_54_k2 = 0.102
reaction_55_k1 = 0.2
reaction_55_k2 = 0.2
reaction_56_k1 = 0.2
reaction_56_k2 = 0.2
reaction_57_k1 = 0.2
reaction_57_k2 = 0.2
reaction_58_k1 = 1.6
reaction_58_k2 = 1.6
reaction_59_k1 = 0.2
reaction_59_k2 = 0.2
reaction_60_k1 = 0.1
reaction_60_k2 = 0.1
reaction_61_k1 = 0.1
reaction_61_k2 = 0.1
reaction_62_k1 = 1.0
reaction_62_k2 = 1.0
reaction_63_k1 = 1.0
reaction_63_k2 = 1.0
reaction_64_k1 = 0.005
reaction_65_k1 = 0.005
reaction_66_v = 2e-05
reaction_67_k1 = 0.1
reaction_68_k1 = 0.1
reaction_69_k1 = 0.1
reaction_70_k1 = 0.1
reaction_70_k2 = 0.1
_29_k1 = 0.0492
_31_Km = 40.0
_31_V = 2.34
_33_k1 = 1.6
_33_k2 = 1.6
_35_k1 = 0.232
_37_k1 = 255.068
_39_Km = 0.53
_39_V = 3.51
_41_k1 = 0.2
_43_k1 = 2.9
_43_k2 = 0.2
_77_k = 9.45
_86_k1 = 0.03333
_86_k2 = 0.03333
_103_k1 = 1.0
_103_k2 = 0.1
_125_k = 1000.0
_125_km = 0.0318
_132_k = 3.51
_132_km = 0.53
_139_k1 = 16.6
_149_k1 = 1000.0
_156_k1 = 0.156
_156_k2 = 0.156
_164_k1 = 0.16
_172_k1 = 0.1
_172_k2 = 0.01
_178_k1 = 1.0
_178_k2 = 0.01
_192_k1 = 1900.0
_194_k1 = 8.69
_194_k2 = 0.01
reaction_1_v = 0.00146
reaction_2_k = 0.0001
reaction_2_k1 = 0.031
reaction_3_k = 0.0001
reaction_3_k1 = 0.1
reaction_4_k = 0.000228
reaction_4_k1 = 0.0285
reaction_5_k = 2e-05
reaction_5_k1 = 0.00055
reaction_6_v = 0.0125
reaction_7_k1 = 1.0
reaction_7_k2 = 0.05288
reaction_8_k1 = 0.156
reaction_8_k2 = 0.336
reaction_9_k1 = 0.027778
reaction_10_k1 = 0.027778
reaction_11_k1 = 0.027778
reaction_12_k1 = 0.03333
reaction_13_v = 0.0156
reaction_14_v = 0.01183
reaction_15_k1 = 0.1266
reaction_16_k1 = 0.065
reaction_17_Km = 3.51
reaction_17_V = 0.53
reaction_18_k1 = 0.232
reaction_19_k1 = 0.2333
reaction_19_k2 = 1.8056
reaction_20_k1 = 0.2
reaction_21_k1 = 0.1
reaction_21_k2 = 0.2
reaction_22_v = 0.04528
reaction_23_k1 = 0.2
reaction_24_Km = 3.51
reaction_24_V = 0.53
reaction_25_Km = 40.0
reaction_25_V = 2.34
reaction_26_Km = 0.53
reaction_26_V = 3.51
reaction_27_k = 1000.0
reaction_27_km = 0.0318
reaction_28_k = 3.51
reaction_28_km = 0.53
reaction_29_k1 = 0.2
reaction_30_k1 = 0.156
reaction_30_k2 = 0.336
_1 = 1.0
_3 = 1.0


#initial values
_101 = 0.0
_105 = 0.0
_11 = 0.0
_129 = 0.0
_13 = 0.0
_147 = 0.0
_15 = 0.0
_153 = 0.0
_174 = 0.0
_181 = 0.0
_19 = 0.0
_198 = 0.0
_21 = 0.0
_25 = 0.0
_27 = 0.0
_5 = 0.0
_75 = 0.0
_79 = 0.0
_84 = 0.0
_9 = 0.0
_96 = 0.0
_99 = 0.0
species_1 = 0.0
species_10 = 0.0
species_11 = 0.0
species_12 = 0.0
species_13 = 0.0
species_14 = 0.0
species_15 = 0.0
species_16 = 0.0
species_17 = 0.0
species_18 = 0.0
species_19 = 0.0
species_2 = 0.0
species_20 = 0.0
species_21 = 0.0
species_22 = 0.0
species_23 = 0.0
species_24 = 0.0
species_25 = 0.0
species_26 = 0.0
species_27 = 0.0
species_28 = 0.0999999951844375
species_29 = 0.0
species_3 = 0.0
species_30 = 0.0
species_31 = 0.0
species_4 = 0.0
species_5 = 0.0
species_6 = 0.0
species_7 = 0.0
species_8 = 0.0
species_9 = 0.0


#assignment rules
!F parameter_2 = species_2 + _11 + species_16 + species_16
!F parameter_4 = _181 + species_1 + _15 + _27
!F parameter_5 = _99 + _105 + _129 + _153 + _9 + _13 + _19 + _21 + species_19
!F parameter_6 = _147 + _153 + species_6 + _5 + _9 + species_18 + _13 + species_16 + species_19 + species_21 + species_27 + species_26 + species_23
!F parameter_9 = _147 + _153 + species_6
!F parameter_10 = species_11 + _5 + _9 + _13 + species_18 + species_16 + species_18 + species_19 + species_21 + species_23 + species_26 + species_26 + species_27
!F parameter_8 = species_3 + species_4 + species_5 + species_6 + species_8 + species_17 + species_18 + species_20 + species_21 + species_26 + species_27
!F parameter_7 = species_4 + species_6 + species_18 + species_20 + species_21 + species_26
!F parameter_3 = _174 + _181 + _198 + _25 + _27