(* Generated by JWS Online *) (* This is an experimental feature of JWS Online. Please report any mistakes.*) (* Note that the following notable SBML entities or features are not supported in notebook outputyet: *) (* Events *) (* Constraints *) (* Units and UnitDefinitions *) (* AlgebraicRules *) (* conversionFactors *) variables = { T[t], TEstar[t], Tstar[t], V[t] }; initialValues = { T[0] == 1000000.0, TEstar[0] == 0.0, Tstar[0] == 0.0, V[0] == 1*^-06 }; rates = { v1, v2, v3, v4, v5, v6, v7, v8, v9 }; rateEquations = { v1 -> lambda, v2 -> d*T[t], v3 -> k*T[t]*V[t], v4 -> b*TEstar[t], v5 -> phi*TEstar[t], v6 -> deltaE*TEstar[t], v7 -> delta*Tstar[t], v8 -> p*Tstar[t], v9 -> c*V[t] }; parameters = { b -> 0.01, c -> 23.0, d -> 0.01, delta -> 1.0, deltaE -> 0.7, k -> 2.4*^-08, lambda -> 10000.0, p -> 4000.0, phi -> 0.8, default -> 1.0 }; assignments = { }; events = { }; speciesAnnotations = { }; reactionAnnotations = { }; units = { {"time" -> "", "metabolite" -> "", "extent" -> ""} }; (* Time evolution *) odes = { T'[t] == 1.0*v1 +1.0*v4 -1.0*v3 -1.0*v2, TEstar'[t] == 1.0*v3 -1.0*v4 -1.0*v5 -1.0*v6, Tstar'[t] == 1.0*v5 -1.0*v7, V'[t] == 1.0*v8 -1.0*v9 }; timeCourse = NDSolve[Join[odes, initialValues]//.rateEquations//.assignments//.parameters, variables, {t, 0, 100}]; (* Steady-state solution initialized with result of time evolution *) findRootEquations = odes /.D[_[t],t]->0; findRootVariables = Partition[Flatten[{#, #/.timeCourse/.t->100} &/@variables],2]; steadyStateVariables = FindRoot[findRootEquations//.rateEquations//.assignments//.parameters, findRootVariables, MaxIterations->100] fluxes = #//.assignments//.parameters/.steadyStateVariables&/@rateEquations (* Plot the time evolution of the variables *) plotTable=Table[Plot[variables[[i]]/.parameters/.timeCourse,{t,0,100},PlotLegends->variables[[i]],PlotRange->Full],{i,Length[variables]}]