begin name
nyman3
end name

begin reactions
v1a {1.0}IR = {1.0}IRins
v1b {1.0}IRins = {1.0}IR
v1c {1.0}IRins = {1.0}IRp
v1d {1.0}IRp = {1.0}IRiP
v1e {1.0}IRiP = {1.0}IRi
v1g {1.0}IRp = {1.0}IR
v1r {1.0}IRi = {1.0}IR
v2 {1.0}IRS = {1.0}IRSiP
v3 {1.0}X = {1.0}Xp
vm2 {1.0}IRSiP = {1.0}IRS
vm3 {1.0}Xp = {1.0}X
end reactions

begin rate equations
v1a = ins*k1a*IR[t] + k1aBasic*IR[t]
v1b = k1b*IRins[t]
v1c = k1c*IRins[t]
v1d = k1d*IRp[t]
v1e = IRiP[t]*(k1e + (k1f*Xp[t])/(1 + Xp[t]))
v1g = k1g*IRp[t]
v1r = k1r*IRi[t]
v2 = (k21*(k22*IRiP[t] + IRp[t])*IRS[t])/(1 + km23*Xp[t])
v3 = k3*IRSiP[t]*X[t]
vm2 = km2*IRSiP[t]
vm3 = km3*Xp[t]
end rate equations

begin parameters
ins = 100.0
k1a = 0.153418
k1aBasic = 0.0383389
k1b = "3.4699e-06"
k1c = 0.574266
k1d = 4.78844
k1e = "5.25027e-05"
k1f = 119.353
k1g = 4.14899
k1r = 37954.7
k21 = 538004.0
k22 = "1.7252e-06"
k3 = "8.62917e-05"
km2 = 262759.0
km23 = 88.9096
km3 = 0.132671
default = 1.0
end parameters

begin initial conditions
IR[0] = IRi
IRS[0] = IRSi
IRSiP[0] = IRSiPi
IRi[0] = IRii
IRiP[0] = IRiPi
IRins[0] = IRinsi
IRp[0] = IRpi
X[0] = Xi
Xp[0] = Xpi
end initial conditions

begin initial values
IRi = 8.94067597532632
IRSi = 9.43998194225544
IRSiPi = 0.560018057744573
IRii = 4.83863890758515e-06
IRiPi = 0.424076631823384
IRinsi = 0.59688996214639
IRpi = 0.0383525925240207
Xi = 9.99635886407151
Xpi = 0.00364113592848386
end initial values

begin assignment rules
IRmem := 10*(IR[t] + IRins[t] + IRp[t])
measIRp := 31.8*(IRiP[t] + IRp[t])
measIRS1 := 21.2*IRSiP[t]
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units