begin name
lee4
end name

begin reactions
r1 {1.0}E + {1.0}P = {1.0}EP1
r10 {1.0}P2 = {1.0}P21
r11 {1.0}E + {1.0}P21 = {1.0}EP21
r12 {1.0}E + {1.0}P2 = {1.0}EP2
r13 {1.0}EP21 = {1.0}E + {1.0}T
r14 {1.0}EP2 = {1.0}E + {1.0}T
r15 {1.0}EP1 = {1.0}T
r16 {1.0}EP2 = {1.0}T
r2 {1.0}EP1 = {1.0}E + {1.0}M
r3 {1.0}M = {1.0}M1
r4 {1.0}E + {1.0}M1 = {1.0}EM1
r5 {1.0}E + {1.0}M = {1.0}EM
r6 {1.0}EM1 = {1.0}E + {1.0}T
r7 {1.0}EM = {1.0}E + {1.0}T
r8 {1.0}E + {1.0}P = {1.0}EP2
r9 {1.0}EP2 = {1.0}E + {1.0}P2
end reactions

begin rate equations
r1 = compartment*(-(j1*EP1[t]) + k1*E[t]*P[t])
r10 = compartment*k10*P2[t]
r11 = compartment*(-(j7*EP21[t]) + k7*E[t]*P21[t])
r12 = compartment*(-(j7a*EP2[t]) + k7a*E[t]*P2[t])
r13 = compartment*k8*EP21[t]
r14 = compartment*k8a*EP2[t]
r15 = compartment*kC1*EP1[t]
r16 = compartment*kC2*EP2[t]
r2 = compartment*k2*EP1[t]
r3 = compartment*k9*M[t]
r4 = compartment*(-(j3*EM1[t]) + k3*E[t]*M1[t])
r5 = compartment*(-(j3a*EM[t]) + k3a*E[t]*M[t])
r6 = compartment*k4*EM1[t]
r7 = compartment*k4a*EM[t]
r8 = compartment*(-(j5*EP2[t]) + k5*E[t]*P[t])
r9 = compartment*k6*EP2[t]
end rate equations

begin parameters
j1 = 33.4
j3 = "1.58e-06"
j3a = 0.185
j5 = 21.8
j7 = "4.46e-09"
j7a = "2.66e-05"
k1 = 91.8
k10 = "7.23e-10"
k2 = 82.4
k3 = 38.1
k3a = 151.5
k4 = 38.1
k4a = 209.9
k5 = 5.16
k6 = 32.3
k7 = "6.76e-08"
k7a = 4.7
k8 = 0.00599
k8a = 42.6
k9 = "3.12e-08"
kC1 = "2.39e-06"
kC2 = 0.031
compartment = 1.0
end parameters

begin initial conditions
E[0] = Ei
EM[0] = EMi
EM1[0] = EM1i
EP1[0] = EP1i
EP2[0] = EP2i
EP21[0] = EP21i
EP1[0] = EP1i
EP2[0] = EP2i
M[0] = Mi
M1[0] = M1i
P[0] = Pi
P2[0] = P2i
P21[0] = P21i
T[0] = Ti
end initial conditions

begin initial values
Ei = 0.00015
EMi = 0.0
EM1i = 0.0
EP1i = 0.0
EP2i = 0.0
EP21i = 0.0
EP1i = 0.0
EP2i = 0.0
Mi = 0.0
M1i = 0.0
Pi = 1.0
P2i = 0.0
P21i = 0.0
Ti = 0.0
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
T http://identifiers.org/chebi/CHEBI:9574
end species annotations

begin units
end units