begin name
kouril7
end name

begin reactions
v1 {1.0}ATP + {1.0}P3G = {1.0}ADP + {1.0}BPG
v2 {1.0}ADP + {1.0}pep = {1.0}ATP + {1.0}pyr
v4 {1.0}NADH + {1.0}BPG = {1.0}NAD + {1.0}gap
v5 {1.0}NAD + {1.0}Glc = {1.0}NADH + {1.0}$GA
end reactions

begin rate equations
v1 = -((VmPGK*(KeqPGK*ADP[t]*BPG[t] - ATP[t]*P3G[t]))/(KmPGKATP*KmPGKP3G*(1 + ADP[t]/KmPGKADP + ATP[t]/KmPGKATP)*(1 + BPG[t]/KmPGKBPG + P3G[t]/KmPGKP3G)))
v2 = kPK*ADP[t]*pep[t]
v4 = -(((VmGAPDHf*gap[t]*NAD[t])/(KmGAPDHGAP*KmGAPDHNAD) - (VmGAPDHr*BPG[t]*NADH[t])/(KmGAPDHBPG*KmGAPDHNADH))/((1 + BPG[t]/KmGAPDHBPG + gap[t]/KmGAPDHGAP)*(1 + NAD[t]/KmGAPDHNAD + NADH[t]/KmGAPDHNADH)))
v5 = kGDH*Glc[t]*NAD[t]
end rate equations

begin parameters
KeqPGK = 3200.0
KmGAPDHBPG = 0.0098
KmGAPDHGAP = 0.21
KmGAPDHNAD = 0.09
KmGAPDHNADH = 0.06
KmPGKADP = 0.2
KmPGKATP = 0.3
KmPGKBPG = 0.003
KmPGKP3G = 0.53
VmGAPDHf = 0.188086
VmGAPDHr = 1.04
VmPGK = 0.038
kGDH = 10.0
kPK = 10.0
GA = 0.0
default = 1.0
end parameters

begin initial conditions
ADP[0] = ADPi
ATP[0] = ATPi
BPG[0] = BPGi
Glc[0] = Glci
NAD[0] = NADi
NADH[0] = NADHi
P3G[0] = P3Gi
gap[0] = gapi
pep[0] = pepi
pyr[0] = pyri
end initial conditions

begin initial values
ADPi = 0.0
ATPi = 10.0
BPGi = 0.0
Glci = 10.0
NADi = 0.0
NADHi = 0.2
P3Gi = 3.0
gapi = 0.365
pepi = 10.0
pyri = 0.15
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units