begin name
kouril4
end name

begin reactions
v1 {1.0}ATP + {1.0}P3G = {1.0}ADP + {1.0}BPG
v2 {1.0}ADP + {1.0}pep = {1.0}ATP + {1.0}pyr
end reactions

begin rate equations
v1 = -((VmPGK*(KeqPGK*ADP[t]*BPG[t] - ATP[t]*P3G[t]))/(KmPGKATP*KmPGKP3G*(1 + ADP[t]/KmPGKADP + ATP[t]/KmPGKATP)*(1 + BPG[t]/KmPGKBPG + P3G[t]/KmPGKP3G)))
v2 = kPK*ADP[t]*pep[t]
end rate equations

begin parameters
KeqPGK = 3200.0
KmPGKADP = 0.2
KmPGKATP = 0.3
KmPGKBPG = 0.003
KmPGKP3G = 0.53
VmPGK = 4.61
kPK = 50.0
default = 1.0
end parameters

begin initial conditions
ADP[0] = ADPi
ATP[0] = ATPi
BPG[0] = BPGi
P3G[0] = P3Gi
pep[0] = pepi
pyr[0] = pyri
end initial conditions

begin initial values
ADPi = 0.0
ATPi = 10.0
BPGi = 0.0
P3Gi = 4.0
pepi = 5.0
pyri = 0.0
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
v1 http://identifiers.org/ec-code/2.7.2.3
v2 http://identifiers.org/ec-code/2.7.1.40
end process annotations

begin species annotations
ADP http://identifiers.org/obo.chebi/CHEBI%3A16761
ADP http://identifiers.org/kegg.compound/C00008
ATP http://identifiers.org/obo.chebi/CHEBI%3A15422
ATP http://identifiers.org/kegg.compound/C00002
BPG http://identifiers.org/obo.chebi/CHEBI%3A16001
BPG http://identifiers.org/kegg.compound/C00236
end species annotations

begin units
end units