begin name
ibrahim3
end name

begin reactions
R1 {1.0}Mad1CMad2 + {1.0}OMad2 = {1.0}Mad1CMad2OMad2
R2 {1.0}Mad1CMad2OMad2 + {1.0}Cdc20 = {1.0}Mad1CMad2 + {1.0}Cdc20CMad2
R3 {1.0}Cdc20CMad2 = {1.0}Cdc20 + {1.0}OMad2
R4 {1.0}Cdc20CMad2 + {1.0}Bub3BubR1 = {1.0}MCC
R5 {1.0}Bub3BubR1 + {1.0}Cdc20 = {1.0}Bub3BubR1Cdc20
R6 {1.0}OMad2 + {1.0}Cdc20 = {1.0}Cdc20CMad2
end reactions

begin rate equations
R1 = Cytoplasm*(-(k1r*Mad1CMad2OMad2[t]) + k1f*u*Mad1CMad2[t]*OMad2[t])
R2 = Cytoplasm*k2f*u*Cdc20[t]*Mad1CMad2OMad2[t]
R3 = Cytoplasm*k3f*Cdc20CMad2[t]
R4 = Cytoplasm*(k4f*u*Bub3BubR1[t]*Cdc20CMad2[t] - k4r*MCC[t])
R5 = Cytoplasm*(-(k5r*Bub3BubR1Cdc20[t]) + k5f*u*Bub3BubR1[t]*Cdc20[t])
R6 = Cytoplasm*kf6*Cdc20[t]*OMad2[t]
end rate equations

begin parameters
constval0 = 0.0
constval1 = 1.0
k1f = 200000.0
k1r = 0.2
k2f = 10000000.0
k3f = 0.01
k4f = 10000000.0
k4r = 0.02
k5f = 10000.0
k5r = 0.2
kf6 = 1000.0
u = 1.0
Cytoplasm = 1.0
end parameters

begin initial conditions
Bub3BubR1[0] = Bub3BubR1i
Bub3BubR1Cdc20[0] = Bub3BubR1Cdc20i
Cdc20[0] = Cdc20i
Cdc20CMad2[0] = Cdc20CMad2i
MCC[0] = MCCi
Mad1CMad2[0] = Mad1CMad2i
Mad1CMad2OMad2[0] = Mad1CMad2OMad2i
OMad2[0] = OMad2i
end initial conditions

begin initial values
Bub3BubR1i = 1.3e-07
Bub3BubR1Cdc20i = 0.0
Cdc20i = 2.2e-07
Cdc20CMad2i = 0.0
MCCi = 0.0
Mad1CMad2i = 5e-08
Mad1CMad2OMad2i = 0.0
OMad2i = 1.3e-07
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
mt_attachment = (t > 2000, {u -> constval0}, 0)
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units