(* Generated by JWS Online *)

(* This is an experimental feature of JWS Online. Please report any mistakes.*)

(* Note that the following notable SBML entities or features are not supported in notebook outputyet: *)
    (* Events *)
    (* Constraints *)
    (* Units and UnitDefinitions *)
    (* AlgebraicRules *)
    (* conversionFactors *)

variables = {
PGKBmRNA[t], PGKBp[t], PGKCmRNA[t], PGKCp[t], precur[t]
};

initialValues = {
PGKBmRNA[0] == 0.0, PGKBp[0] == 0.0, PGKCmRNA[0] == 0.0, PGKCp[0] == 0.0, precur[0] == 0.0
};

rates = {
v\[LetterSpace]1, v\[LetterSpace]10, v\[LetterSpace]11, v\[LetterSpace]12, v\[LetterSpace]13, v\[LetterSpace]14, v\[LetterSpace]2, v\[LetterSpace]3, v\[LetterSpace]4, v\[LetterSpace]5, v\[LetterSpace]6, v\[LetterSpace]7, v\[LetterSpace]8, v\[LetterSpace]9
};

rateEquations = {
v\[LetterSpace]1 -> vtranscr, v\[LetterSpace]10 -> ktransl*nribo*PGKCmRNA[t], v\[LetterSpace]11 -> mu*PGKBp[t], v\[LetterSpace]12 -> mu*PGKCp[t], v\[LetterSpace]13 -> kdegrpB*PGKBp[t], v\[LetterSpace]14 -> kdegrpC*PGKCp[t], v\[LetterSpace]2 -> ksplic*precur[t], v\[LetterSpace]3 -> kdegrp*precur[t], v\[LetterSpace]4 -> mu*precur[t], v\[LetterSpace]5 -> mu*PGKBmRNA[t], v\[LetterSpace]6 -> kdegrB*PGKBmRNA[t], v\[LetterSpace]7 -> mu*PGKCmRNA[t], v\[LetterSpace]8 -> kdegrC*PGKCmRNA[t], v\[LetterSpace]9 -> ktransl*nribo*PGKBmRNA[t]
};

parameters = {
kdegrB -> 0.092, kdegrC -> 0.015, kdegrp -> 0.08, kdegrpB -> 1*^-20, kdegrpC -> 1*^-20, ksplic -> 0.41, ktransl -> 13.4, mu -> 0.0019, nribo -> 12.0, vtranscr -> 0.24, ext -> 0.0, default\[LetterSpace]compartment -> 1.0
};

assignments = {

};

events = {

};

speciesAnnotations = {

};

reactionAnnotations = {

};

units = {
{"time" -> "", "metabolite" -> "", "extent" -> ""}
};

(* Time evolution *)
odes = {
PGKBmRNA'[t] == 1.0*v\[LetterSpace]2 -1.0*v\[LetterSpace]6 -1.0*v\[LetterSpace]5, PGKBp'[t] == 1.0*v\[LetterSpace]9 -1.0*v\[LetterSpace]11 -1.0*v\[LetterSpace]13, PGKCmRNA'[t] == 1.0*v\[LetterSpace]2 -1.0*v\[LetterSpace]8 -1.0*v\[LetterSpace]7, PGKCp'[t] == 1.0*v\[LetterSpace]10 -1.0*v\[LetterSpace]12 -1.0*v\[LetterSpace]14, precur'[t] == 1.0*v\[LetterSpace]1 -1.0*v\[LetterSpace]4 -1.0*v\[LetterSpace]2 -1.0*v\[LetterSpace]3
};
timeCourse = NDSolve[Join[odes, initialValues]//.rateEquations//.assignments//.parameters, variables, {t, 0, 100}];

(* Steady-state solution initialized with result of time evolution *)
findRootEquations = odes /.D[_[t],t]->0;
findRootVariables = Partition[Flatten[{#, #/.timeCourse/.t->100} &/@variables],2];
steadyStateVariables = FindRoot[findRootEquations//.rateEquations//.assignments//.parameters, findRootVariables, MaxIterations->100]
fluxes = #//.assignments//.parameters/.steadyStateVariables&/@rateEquations

(* Plot the time evolution of the variables *)
plotTable=Table[Plot[variables[[i]]/.parameters/.timeCourse,{t,0,100},PlotLegends->variables[[i]],PlotRange->Full],{i,Length[variables]}]