begin name
goldbeter4
end name

begin reactions
R0 {1.0}$EXTERNAL = {1.0}Z
R1 {1.0}$EXTERNAL = {1.0}Z
R2 {1.0}Z = {1.0}Y
R3 {1.0}Y = {1.0}Z
Reff {1.0}Z = {1.0}$EXTERNAL
Rf {1.0}Y = {1.0}Z
end reactions

begin rate equations
R0 = cytosol*v0
R1 = beta*cytosol*v1
R2 = (cytosol*Vm2*Z[t]^n)/(K2^n + Z[t]^n)
R3 = (store*Vm3*Y[t]^m*Z[t]^p)/((Kr^m + Y[t]^m)*(Ka^p + Z[t]^p))
Reff = cytosol*k*Z[t]
Rf = kf*store*Y[t]
end rate equations

begin parameters
K2 = 1.0
Ka = 0.9
Kr = 2.0
Vm2 = 65.0
Vm3 = 500.0
beta = 0.301
k = 10.0
kf = 1.0
m = 2.0
n = 2.0
p = 4.0
v0 = 1.0
v1 = 7.3
cytosol = 1.0
store = 1.0
end parameters

begin initial conditions
Y[0] = Yi
Z[0] = Zi
end initial conditions

begin initial values
Yi = 1.6
Zi = 0.15
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
R0 http://identifiers.org/go/GO:0006816
R1 http://identifiers.org/go/GO:0005220
R2 http://identifiers.org/go/GO:0032470
R3 http://identifiers.org/go/GO:0007204
R3 http://identifiers.org/go/GO:0048763
R_eff http://identifiers.org/go/GO:0006816
Rf http://identifiers.org/go/GO:0007204
end process annotations

begin species annotations
Y http://identifiers.org/chebi/CHEBI:29108
Y http://identifiers.org/kegg.compound/C00076
Z http://identifiers.org/chebi/CHEBI:29108
Z http://identifiers.org/kegg.compound/C00076
end species annotations

begin units
end units