#gardner1



#reactions
reaction1:
 $pool = {1.0}C
  vi
reaction10:
 {1.0}Z = {1.0}C
  alpha * d1 * Z
reaction11:
 {1.0}Z = {1.0}Y
  alpha * kd * Z
reaction12:
 $pool = {1.0}Y
  vs
reaction13:
 {1.0}Y = $pool
  d1 * Y
reaction2:
 {1.0}C = $pool
  C * k1 * X * pow(C + K5, -1)
reaction3:
 {1.0}C = $pool
  C * kd
reaction4:
 $pool = {1.0}M
  (1 + -1 * M) * V1 * pow(K1 + -1 * M + 1, -1)
reaction5:
 {1.0}M = $pool
  M * V2 * pow(K2 + M, -1)
reaction6:
 $pool = {1.0}X
  V3 * (1 + -1 * X) * pow(K3 + -1 * X + 1, -1)
reaction7:
 {1.0}X = $pool
  V4 * X * pow(K4 + X, -1)
reaction8:
 {1.0}C + {1.0}Y = {1.0}Z
  a1 * C * Y
reaction9:
 {1.0}Z = {1.0}C + {1.0}Y
  a2 * Z


#parameters
K6 = 0.3
V1p = 0.75
V3p = 0.3
reaction1_vi = 0.1
reaction2_k1 = 0.5
reaction2_K5 = 0.02
reaction3_kd = 0.02
reaction4_K1 = 0.1
reaction5_V2 = 0.25
reaction5_K2 = 0.1
reaction6_K3 = 0.2
reaction7_K4 = 0.1
reaction7_V4 = 0.1
reaction8_a1 = 0.05
reaction9_a2 = 0.05
reaction10_alpha = 0.1
reaction10_d1 = 0.05
reaction11_kd = 0.02
reaction11_alpha = 0.1
reaction12_vs = 0.2
reaction13_d1 = 0.05
Cell = 1.0


#initial values
C = 0.0
M = 0.0
X = 0.0
Y = 0.0
Z = 0.0


#assignment rules
!F V3 = M * V3p
!F V1 = C * V1p * pow(C + K6, -1.0)