begin name
ferreira1
end name

begin reactions
v1a {1.0}Lysine + {1.0}Glucose = {1.0}Schiff
v1b {1.0}Schiff = {1.0}Lysine + {1.0}Glucose
v2a {1.0}Schiff = {1.0}Amadori
v2b {1.0}Amadori = {1.0}Schiff
v3 {1.0}Glucose = {1.0}Glyoxal
v4 {1.0}Amadori = {1.0}CML
v5 {1.0}Lysine + {1.0}Glyoxal = {1.0}CML
v5b {1.0}Glyoxal = {1.0}$EXTERNAL
v6 {1.0}Schiff = {1.0}CML
v7a {1.0}$EXTERNAL = {1.0}Lysine
v7b {1.0}$EXTERNAL = {1.0}Glyoxal
v7c {1.0}Schiff = {1.0}$EXTERNAL
end reactions

begin rate equations
v1a = compartment*v1ak1a*v1ap1*Glucose[t]*Lysine[t]
v1b = compartment*v1bk1b*Schiff[t]
v2a = compartment*v2ak2a*v2ap2*Schiff[t]
v2b = compartment*v2bk2b*v2bp2*Amadori[t]
v3 = 1.6471820345351462*compartment*v3k3*v3ox*v3p3*Glucose[t]^0.36
v4 = compartment*v4k4*v4ox*v4p4*Amadori[t]
v5 = compartment*v5k5*v5ox*v5p5*Glyoxal[t]*Lysine[t]
v5b = compartment*v5bk5b*Glyoxal[t]
v6 = 1.6471820345351462*compartment*v6k3*v6ox*v6p6*Schiff[t]^0.36
v7a = 0.08235910172675731*compartment*v7ak3*v7aox*v7ap7*Schiff[t]^0.36
v7b = 0.00823591017267573*compartment*v7bk3*v7box*v7bp7*Schiff[t]^0.36
v7c = 1.6471820345351462*compartment*v7ck3*v7cox*v7cp7*Schiff[t]^0.36
end rate equations

begin parameters
v1ap1 = 0.115
v1ak1a = 0.09
v1bk1b = 0.36
v2ap2 = 0.75
v2ak2a = 0.033
v2bp2 = 0.75
v2bk2b = 0.0012
v3ox = 1.0
v3p3 = 1.0
v3k3 = "7.92e-07"
v4ox = 1.0
v4p4 = 1.0
v4k4 = "8.6e-05"
v5ox = 1.0
v5p5 = 1.0
v5k5 = 0.019
v5bk5b = 0.0017
v6ox = 1.0
v6p6 = 2.7
v6k3 = "7.92e-07"
v7aox = 1.0
v7ap7 = 60.0
v7ak3 = "7.92e-07"
v7box = 1.0
v7bp7 = 60.0
v7bk3 = "7.92e-07"
v7cox = 1.0
v7cp7 = 60.0
v7ck3 = "7.92e-07"
compartment = 1.0
end parameters

begin initial conditions
Amadori[0] = Amadorii
CML[0] = CMLi
Glucose[0] = Glucosei
Glyoxal[0] = Glyoxali
Lysine[0] = Lysinei
Schiff[0] = Schiffi
end initial conditions

begin initial values
Amadorii = 0.0
CMLi = 0.0
Glucosei = 0.25
Glyoxali = 0.0
Lysinei = 0.0034
Schiffi = 0.0
end initial values

begin assignment rules
FractionAmadori := 294.11764705882354*Amadori[t]
FractionCML := 294.11764705882354*CML[t]
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
Glucose http://identifiers.org/chebi/CHEBI:17234
Glucose http://identifiers.org/kegg.compound/C00293
Glyoxal http://identifiers.org/kegg.compound/C14448
Glyoxal http://identifiers.org/chebi/CHEBI:34779
Lysine http://identifiers.org/chebi/CHEBI:25094
end species annotations

begin units
end units