#curien1

FIX: Cys Cystathionine Hser Phi Thr

#reactions
v_1:
 {1.0}Hser = {1.0}Phser
  V1
v_2:
 {1.0}Phser + {1.0}Cys = {1.0}Cystathionine + {1.0}Phi
  CGS*(kcat2/(1+KmCYS/Cys))*Phser/(Phser+KmPHSER*(1+Phi/Ki2)/(1+KmCYS/Cys))
v_3:
 {1.0}Phser = {1.0}Thr + {1.0}Phi
  TS*((0.42 + 3.5*AdoMet**2/73)/(1+AdoMet**2/73))*Phser/(((1+Phi/Ki3)*(250*(1+AdoMet/0.5)/(1+AdoMet/1.09))/(1+AdoMet**2/142))+Phser)


#parameters
AdoMet = 20.0
CGS = 0.7
Ki2 = 2000.0
Ki3 = 1000.0
KmCYS = 460.0
KmPHSER = 2500.0
TS = 5.0
V1 = 1.0
kcat2 = 30.0
Cys = 15.0
Cystathionine = 0.0
Hser = 0.0
Phi = 10000.0
Thr = 0.0
default_compartment = 1.0


#initial values
Phser = 0.0


#assignment rules