begin name
curien1
end name

begin reactions
v1 {1.0}$Hser = {1.0}Phser
v2 {1.0}Phser + {1.0}$Cys = {1.0}$Cystathionine + {1.0}$Phi
v3 {1.0}Phser = {1.0}$Thr + {1.0}$Phi
end reactions

begin rate equations
v1 = V1
v2 = (CGS*kcat2*Phser[t])/((1 + KmCYS/Cys)*((KmPHSER*(1 + Phi/Ki2))/(1 + KmCYS/Cys) + Phser[t]))
v3 = ((0.42 + 0.04794520547945205*AdoMet^2)*TS*Phser[t])/((1 + AdoMet^2/73)*((250*(1 + 2.*AdoMet)*(1 + Phi/Ki3))/((1 + 0.9174311926605504*AdoMet)*(1 + AdoMet^2/142)) + Phser[t]))
end rate equations

begin parameters
AdoMet = 20.0
CGS = 0.7
Ki2 = 2000.0
Ki3 = 1000.0
KmCYS = 460.0
KmPHSER = 2500.0
TS = 5.0
V1 = 1.0
kcat2 = 30.0
Cys = 15.0
Cystathionine = 0.0
Hser = 0.0
Phi = 10000.0
Thr = 0.0
defaultcompartment = 1.0
end parameters

begin initial conditions
Phser[0] = Phseri
end initial conditions

begin initial values
Phseri = 0.0
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
Cys http://identifiers.org/obo.chebi/CHEBI%3A32460
Cystathionine http://identifiers.org/kegg.compound/C00542
Thr http://identifiers.org/obo.chebi/CHEBI%3A32835
end species annotations

begin units
end units