begin name chan1 end name begin reactions v1 {1.0}$EXTERNAL = {1.0}lckinactive v10 {1.0}phosphataseactive = {1.0}$EXTERNAL v2 {1.0}lckactive = {1.0}lckinactive v3 {1.0}lckinactive = {1.0}lckactive v4 {1.0}lckinactive = {1.0}lckactive v5 {1.0}lckinactive = {1.0}$EXTERNAL v6 {1.0}lckactive = {1.0}$EXTERNAL v7 {1.0}phosphataseinactive = {1.0}phosphataseactive v8 {1.0}phosphataseinactive = {1.0}phosphataseactive v9 {1.0}phosphataseactive = {1.0}phosphataseinactive end reactions begin rate equations v1 = rl v10 = d2*phosphataseactive[t] v2 = n1*lckactive[t]*phosphataseactive[t] v3 = k1*lckinactive[t] v4 = m1*lckactive[t]^n*lckinactive[t] v5 = d0*lckinactive[t] v6 = d1*lckactive[t] v7 = k2*phosphataseinactive[t] v8 = m2*lckactive[t]*phosphataseinactive[t] v9 = n2*phosphataseactive[t] end rate equations begin parameters d0 = 0.15 d1 = 0.15 d2 = 0.0 k1 = 0.01 k2 = 0.01 m1 = 1.0 m2 = 1.0 n = 1.95 n1 = 1.0 n2 = 0.02 rl = 0.0 compartment = 1.0 end parameters begin initial conditions lckactive[0] = lckactivei lckinactive[0] = lckinactivei phosphataseactive[0] = phosphataseactivei phosphataseinactive[0] = phosphataseinactivei end initial conditions begin initial values lckactivei = 0.0 lckinactivei = 0.0 phosphataseactivei = 0.6 phosphataseinactivei = 0.6 end initial values begin assignment rules lcktotal := lckactive[t] + lckinactive[t] end assignment rules begin function definitions end function definitions begin events event_0000001 = (t >= 10, {rl -> 1}, 0) event_0000002 = (t >= 24, {rl -> 0}, 0) end events begin process annotations v2 http://identifiers.org/ec-code/3.1.3.48 v2 http://identifiers.org/go/GO:0004725 end process annotations begin species annotations end species annotations begin units end units