#becker2



#reactions
reaction_1:
 $pool = {1.0}EpoR
  kt * Bmax_SAv * cell
reaction_2:
 {1.0}EpoR = $pool
  kt * EpoR * cell
reaction_3:
 {1.0}SAv + {1.0}EpoR = {1.0}SAv_EpoR
  kon_SAv * SAv * EpoR * cell
reaction_4:
 {1.0}SAv_EpoR = {1.0}SAv + {1.0}EpoR
  koff_SAv * SAv_EpoR * cell
reaction_5:
 {1.0}SAv_EpoR = {1.0}SAv_EpoRi
  kt * SAv_EpoR * cell
reaction_6:
 {1.0}SAv_EpoRi = {1.0}SAv
  kex_SAv * SAv_EpoRi * cell
reaction_7:
 {1.0}SAv_EpoRi = {1.0}dSAvi
  kdi * SAv_EpoRi * cell
reaction_8:
 {1.0}SAv_EpoRi = {1.0}dSAve
  kde * SAv_EpoRi * cell


#parameters
Bmax_SAv = 76.0
kde = 0.0164042
kdi = 0.00317871
kex_SAv = 0.01101
koff_SAv = 0.00679946
kon_SAv = 2.29402e-06
kt = 0.0329366
cell = 1.0
cellsurface = 1.0
medium = 1.0


#initial values
EpoR = 76.0
SAv = 999.293
SAv_EpoR = 0.0
SAv_EpoRi = 0.0
dSAve = 0.0
dSAvi = 0.0


#assignment rules
!F SAv_cells = SAv_EpoRi + dSAvi
!F SAv_medium = SAv + dSAve