#achcar1

FIX: Glce Glye Pig Pyre

#reactions
AKc:
 {2.0}ADPc = {1.0}AMPc + {1.0}ATPc
  (AKcAKck1 * pow(ADPc, 2) - AKcAKck2 * AMPc * ATPc) / cytosol
AKg:
 {44.5116}ADPg = {22.2558}AMPg + {22.2558}ATPg
  (AKgAKgk1 * pow(ADPg, 2) - AKgAKgk2 * AMPg * ATPg) / cytosol
ALDg:
 {22.2558}Fru16BPg = {22.2558}DHAPg + {22.2558}GA3Pg
  ALDgALDgVmax * Fru16BPg * (1 - DHAPg * GA3Pg / (ALDgALDgKeq * Fru16BPg)) / (ALDgALDgKmFru16BP * cytosol * (1 + ADPg / ALDgALDgKiADP + AMPg / ALDgALDgKiAMP + ATPg / ALDgALDgKiATP) * (1 + DHAPg / ALDgALDgKmDHAP + Fru16BPg / (ALDgALDgKmFru16BP * (1 + ADPg / ALDgALDgKiADP + AMPg / ALDgALDgKiAMP + ATPg / ALDgALDgKiATP)) + GA3Pg / ALDgALDgKmGA3P + DHAPg * GA3Pg / (ALDgALDgKmDHAP * ALDgALDgKmGA3P) + Fru16BPg * GA3Pg / (ALDgALDgKiGA3P * ALDgALDgKmFru16BP * (1 + ADPg / ALDgALDgKiADP + AMPg / ALDgALDgKiAMP + ATPg / ALDgALDgKiATP))))
ATPuc:
 {1.0}ATPc = {1.0}ADPc
  ATPucATPuck * ATPc / (cytosol * ADPc)
ENOc:
 {1.0}PGA2c = {1.0}PEPc
  ENOcENOcVmax * (1 - PEPc / (ENOcENOcKeq * PGA2c)) * PGA2c / (cytosol * ENOcENOcKmPGA2 * (1 + PEPc / ENOcENOcKmPEP + PGA2c / ENOcENOcKmPGA2))
G3PDHg:
 {22.2558}DHAPg + {22.2558}NADHg = {22.2558}Gly3Pg + {22.2558}NADg
  G3PDHgG3PDHgVmax * DHAPg * NADHg * (1 - Gly3Pg * NADg / (G3PDHgG3PDHgKeq * DHAPg * NADHg)) / (cytosol * G3PDHgG3PDHgKmDHAP * G3PDHgG3PDHgKmNADH * (1 + DHAPg / G3PDHgG3PDHgKmDHAP + Gly3Pg / G3PDHgG3PDHgKmGly3P) * (1 + NADHg / G3PDHgG3PDHgKmNADH + NADg / G3PDHgG3PDHgKmNAD))
GAPDHg:
 {1.0}Pig + {22.2558}GA3Pg + {22.2558}NADg = {22.2558}BPGA13g + {22.2558}NADHg
  GAPDHgGAPDHgVmax * GA3Pg * NADg * (1 - NADHg * BPGA13g / (GAPDHgGAPDHgKeq * GA3Pg * NADg)) / (cytosol * GAPDHgGAPDHgKmGA3P * GAPDHgGAPDHgKmNAD * (1 + NADHg / GAPDHgGAPDHgKmNADH + NADg / GAPDHgGAPDHgKmNAD) * (1 + GA3Pg / GAPDHgGAPDHgKmGA3P + BPGA13g / GAPDHgGAPDHgKmBPGA13))
GDAg:
 {1.0}DHAPc + {22.2558}Gly3Pg = {1.0}Gly3Pc + {22.2558}DHAPg
  (-(GDAgGDAgk * DHAPg * Gly3Pc) + GDAgGDAgk * DHAPc * Gly3Pg) / cytosol
GKg:
 {22.2558}ADPg + {22.2558}Gly3Pg = {22.2558}ATPg + {22.2558}Glyg
  GKgGKgVmax * ADPg * Gly3Pg * (1 - ATPg * Glyg / (GKgGKgKeq * ADPg * Gly3Pg)) / (cytosol * GKgGKgKmADP * GKgGKgKmGly3P * (1 + ADPg / GKgGKgKmADP + ATPg / GKgGKgKmATP) * (1 + Gly3Pg / GKgGKgKmGly3P + Glyg / GKgGKgKmGly))
GPOc:
 {1.0}Gly3Pc = {1.0}DHAPc
  GPOcGPOcVmax * Gly3Pc / (cytosol * GPOcGPOcKmGly3P * (1 + (1 + SHAM / GPOcGPOcKiSHAM) * Gly3Pc / GPOcGPOcKmGly3P))
GlcTc:
 {1.0}Glce = {1.0}Glcc
  GlcTcGlcTcVmax * (Glce - Glcc) / (cytosol * (GlcTcGlcTcKmGlc + Glce + Glcc + GlcTcGlcTcalpha * Glce * Glcc / GlcTcGlcTcKmGlc))
GlcTg:
 {1.0}Glcc = {22.2558}Glcg
  (GlcTgGlcTgk * Glcc - GlcTgGlcTgk * Glcg) / cytosol
GlyTc:
 {1.0}Glyc = {1.0}Glye
  (GlyTcGlyTck * (-Glye + Glyc) + GlyTcGlyTcVrmax * GlyTcGlyTcy * (-Glye + Glyc) / (GlyTcGlyTcKmGlye * GlyTcGlyTcy + GlyTcGlyTcy * Glye + Glyc + GlyTcGlyTcx * (1 - GlyTcGlyTcx + GlyTcGlyTcy) * Glye * Glyc / (GlyTcGlyTcKmGlye * GlyTcGlyTcy))) / cytosol
Glytg:
 {22.2558}Glyg = {1.0}Glyc
  GlytgGlytgk * (-Glyc + Glyg) / cytosol
HXKg:
 {22.2558}ATPg + {22.2558}Glcg = {22.2558}ADPg + {22.2558}Glc6Pg
  HXKgHXKgVmax * ATPg * (1 - ADPg * Glc6Pg / (HXKgHXKgKeq * ATPg * Glcg)) * Glcg / (cytosol * HXKgHXKgKmATP * HXKgHXKgKmGlc * (1 + ADPg / HXKgHXKgKmADP + ATPg / HXKgHXKgKmATP) * (1 + Glc6Pg / HXKgHXKgKmGlc6P + Glcg / HXKgHXKgKmGlc))
PFKg:
 {22.2558}ATPg + {22.2558}Fru6Pg = {22.2558}ADPg + {22.2558}Fru16BPg
  PFKgPFKgKi1 * PFKgPFKgVmax * ATPg * (1 - ADPg * Fru16BPg / (PFKgPFKgKeq * ATPg * Fru6Pg)) * Fru6Pg / (cytosol * PFKgPFKgKmATP * PFKgPFKgKmFru6P * (PFKgPFKgKi1 + Fru16BPg) * (PFKgPFKgKsATP / PFKgPFKgKmATP + ADPg / PFKgPFKgKmADP + ATPg / PFKgPFKgKmATP + ADPg * Fru16BPg / (PFKgPFKgKi2 * PFKgPFKgKmADP) + Fru6Pg / PFKgPFKgKmFru6P + ATPg * Fru6Pg / (PFKgPFKgKmATP * PFKgPFKgKmFru6P)))
PGA3Tg:
 {22.2558}PGA3g = {1.0}PGA3c
  (-(PGA3TgPGA3Tgk * PGA3c) + PGA3TgPGA3Tgk * PGA3g) / cytosol
PGAMc:
 {1.0}PGA3c = {1.0}PGA2c
  PGAMcPGAMcVmax * (1 - PGA2c / (PGAMcPGAMcKeq * PGA3c)) * PGA3c / (cytosol * PGAMcPGAMcKmPGA3 * (1 + PGA2c / PGAMcPGAMcKmPGA2 + PGA3c / PGAMcPGAMcKmPGA3))
PGIg:
 {22.2558}Glc6Pg = {22.2558}Fru6Pg
  PGIgPGIgVmax * (1 - Fru6Pg / (PGIgPGIgKeq * Glc6Pg)) * Glc6Pg / (cytosol * PGIgPGIgKmGlc6P * (1 + Fru6Pg / PGIgPGIgKmFru6P + Glc6Pg / PGIgPGIgKmGlc6P))
PGKg:
 {22.2558}BPGA13g + {22.2558}ADPg = {22.2558}PGA3g + {22.2558}ATPg
  PGKgPGKgVmax * ADPg * BPGA13g * (1 - ATPg * PGA3g / (PGKgPGKgKeq * ADPg * BPGA13g)) / (cytosol * PGKgPGKgKmADP * PGKgPGKgKmBPGA13 * (1 + ADPg / PGKgPGKgKmADP + ATPg / PGKgPGKgKmATP) * (1 + BPGA13g / PGKgPGKgKmBPGA13 + PGA3g / PGKgPGKgKmPGA3))
PYKc:
 {1.0}ADPc + {1.0}PEPc = {1.0}ATPc + {1.0}Pyrc
  PYKcPYKcVmax * ADPc * pow(PEPc / (PYKcPYKcKmPEP * (1 + ADPc / PYKcPYKcKiADP + ATPc / PYKcPYKcKiATP)), PYKcPYKcn) * (1 - ATPc * Pyrc / (PYKcPYKcKeq * ADPc * PEPc)) / (cytosol * PYKcPYKcKmADP * (1 + ADPc / PYKcPYKcKmADP + ATPc / PYKcPYKcKmATP) * (1 + pow(PEPc / (PYKcPYKcKmPEP * (1 + ADPc / PYKcPYKcKiADP + ATPc / PYKcPYKcKiATP)), PYKcPYKcn) + Pyrc / PYKcPYKcKmPyr))
PyrTc:
 {1.0}Pyrc = {1.0}Pyre
  PyrTcPyrTcVmax * Pyrc / (cytosol * PyrTcPyrTcKmPyr * (1 + Pyrc / PyrTcPyrTcKmPyr))
TPIg:
 {22.2558}DHAPg = {22.2558}GA3Pg
  TPIgTPIgVmax * DHAPg * (1 - GA3Pg / (TPIgTPIgKeq * DHAPg)) / (cytosol * TPIgTPIgKmDHAP * (1 + DHAPg / TPIgTPIgKmDHAP + GA3Pg / TPIgTPIgKmGA3P))


#parameters
AKcAKck1 = 442.0
AKcAKck2 = 1000.0
AKgAKgk1 = 442.0
AKgAKgk2 = 1000.0
ALDgALDgKeq = 0.084
ALDgALDgKiADP = 1.51
ALDgALDgKiAMP = 3.65
ALDgALDgKiATP = 0.68
ALDgALDgKiGA3P = 0.098
ALDgALDgKmDHAP = 0.015
ALDgALDgKmFru16BP = 0.009
ALDgALDgKmGA3P = 0.067
ALDgALDgVmax = 560.0
ATPucATPuck = 50.0
ENOcENOcKeq = 4.12
ENOcENOcKmPEP = 0.24
ENOcENOcKmPGA2 = 0.054
ENOcENOcVmax = 598.0
EXTERNAL = 0.0
G3PDHgG3PDHgKeq = 17085.0
G3PDHgG3PDHgKmDHAP = 0.1
G3PDHgG3PDHgKmGly3P = 2.0
G3PDHgG3PDHgKmNAD = 0.4
G3PDHgG3PDHgKmNADH = 0.01
G3PDHgG3PDHgVmax = 465.0
GAPDHgGAPDHgKeq = 0.066
GAPDHgGAPDHgKmBPGA13 = 0.1
GAPDHgGAPDHgKmGA3P = 0.15
GAPDHgGAPDHgKmNAD = 0.45
GAPDHgGAPDHgKmNADH = 0.02
GAPDHgGAPDHgVmax = 720.9
GDAgGDAgk = 600.0
GKgGKgKeq = 0.000837
GKgGKgKmADP = 0.56
GKgGKgKmATP = 0.24
GKgGKgKmGly = 0.44
GKgGKgKmGly3P = 3.83
GKgGKgVmax = 200.0
GPOcGPOcKiSHAM = 0.021
GPOcGPOcKmGly3P = 1.7
GPOcGPOcVmax = 368.0
GlcTcGlcTcKmGlc = 1.1
GlcTcGlcTcVmax = 111.7
GlcTcGlcTcalpha = 0.75
GlcTgGlcTgk = 250000.0
GlyTcGlyTcKmGlye = 0.17
GlyTcGlyTcVrmax = 85.0
GlyTcGlyTck = 8.5
GlyTcGlyTcx = 1.0
GlyTcGlyTcy = 1.0
GlytgGlytgk = 1000.0
HXKgHXKgKeq = 759.0
HXKgHXKgKmADP = 0.126
HXKgHXKgKmATP = 0.116
HXKgHXKgKmGlc = 0.1
HXKgHXKgKmGlc6P = 12.0
HXKgHXKgVmax = 1929.0
O2c = 1.0
PFKgPFKgKeq = 1035.0
PFKgPFKgKi1 = 15.8
PFKgPFKgKi2 = 10.7
PFKgPFKgKmADP = 1.0
PFKgPFKgKmATP = 0.0648
PFKgPFKgKmFru6P = 0.999
PFKgPFKgKsATP = 0.0393
PFKgPFKgVmax = 1708.0
PGA3TgPGA3Tgk = 250.0
PGAMcPGAMcKeq = 0.17
PGAMcPGAMcKmPGA2 = 0.16
PGAMcPGAMcKmPGA3 = 0.15
PGAMcPGAMcVmax = 225.0
PGIgPGIgKeq = 0.46
PGIgPGIgKmFru6P = 0.12
PGIgPGIgKmGlc6P = 0.4
PGIgPGIgVmax = 1305.0
PGKgPGKgKeq = 3376.0
PGKgPGKgKmADP = 0.1
PGKgPGKgKmATP = 0.29
PGKgPGKgKmBPGA13 = 0.003
PGKgPGKgKmPGA3 = 1.62
PGKgPGKgVmax = 2862.0
PYKcPYKcKeq = 10800.0
PYKcPYKcKiADP = 0.64
PYKcPYKcKiATP = 0.57
PYKcPYKcKmADP = 0.114
PYKcPYKcKmATP = 15.0
PYKcPYKcKmPEP = 0.34
PYKcPYKcKmPyr = 50.0
PYKcPYKcVmax = 1020.0
PYKcPYKcn = 2.5
PyrTcPyrTcKmPyr = 1.96
PyrTcPyrTcVmax = 230.0
SHAM = 0.0
TPIgTPIgKeq = 0.046
TPIgTPIgKmDHAP = 1.2
TPIgTPIgKmGA3P = 0.25
TPIgTPIgVmax = 999.3
cytosol = 5.4549
default = 1.0
glycosome = 0.2451
Glce = 5.0
Glye = 1e-06
Pig = 0.0
Pyre = 0.0
default_compartment = 1.0


#initial values
ADPc = 1.0
ADPg = 1.0
AMPc = 0.1
AMPg = 0.1
ATPc = 4.9
ATPg = 4.9
BPGA13g = 0.4
DHAPc = 4.6
DHAPg = 4.6
Fru16BPg = 13.0
Fru6Pg = 0.2
GA3Pg = 0.14
Glc6Pg = 0.8
Glcc = 0.01
Glcg = 0.01
Gly3Pc = 1.5
Gly3Pg = 1.5
Glyc = 1e-06
Glyg = 1e-06
NADHg = 0.1
NADg = 3.9
PEPc = 1.4
PGA2c = 0.5
PGA3c = 17.0
PGA3g = 17.0
Pyrc = 14.0


#assignment rules