Info! This is a derivative of the model achcar12

nyabadza3

v_1

EXT = Sn

v_10

v_10

Ins = An

v_11

Ss = Is

v_12

Is = EXT

v_13

Is = It

v_14

Is = As

v_15

It = EXT

v_16

It = As

v_17

An = EXT

v_18

An = EXT

v_19

As = EXT

v_2

Sn = Ins

v_20

As = EXT

v_3

Sn = EXT

v_4

Sn = Ss

v_5

EXT = Ss

v_6

Ss = Ins

v_7

Ss = EXT

v_8

Ins = EXT

v_9

Ins = Is

Global parameters

Assignment rules

Lambda = c*(1.0 - Theta)*Beta*exp ((-m*(Delta_1*An + Delta_2*As))/(Sn + Ss + Ins + Is + It + An + As))*((Ins + Eta_1*(Is + Phi_1*It) + Eta_2*(An + Phi_2*As))/(Sn + Ss + Ins + Is + It + An + As))

people_with_HIV = Ins + Is +It

Function definitions

Note that constraints are not enforced in simulations. It remains the responsibility of the user to verify that simulation results satisfy these constraints.


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Modelling HIV/AIDS in the presence of an HIV testing and screening campaign.

  • F Nyabadza
  • Z Mukandavire
J. Theor. Biol. 2011; 280 (1): 167-179
Abstract
Preventing and managing the HIV/AIDS epidemic in South Africa will dominate the next decade and beyond. Reduction of new HIV infections by implementing a comprehensive national HIV prevention programme at a sufficient scale to have real impact remains a priority. In this paper, a deterministic HIV/AIDS model that incorporates condom use, screening through HIV counseling and testing (HCT), regular testing and treatment as control strategies is proposed with the objective of quantifying the effectiveness of HCT in preventing new infections and predicting the long-term dynamics of the epidemic. It is found that a backward bifurcation occurs if the rate of screening is below a certain threshold, suggesting that the classical requirement for the basic reproduction number to be below unity though necessary, is not sufficient for disease control in this case. The global stabilities of the equilibria under certain conditions are determined in terms of the model reproduction number R(0). Numerical simulations are performed and the model is fitted to data on HIV prevalence in South Africa. The effects of changes in some key epidemiological parameters are investigated. Projections are made to predict the long-term dynamics of the disease. The epidemiological implications of such projections on public health planning and management are discussed.

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