$\mathrm{ConcPEPRBC}\mathrm{Vrbc}$ $\mathrm{ConcATPRBC}\mathrm{Vrbc}$ $\mathrm{ConcRu5PRBC}\mathrm{Vrbc}$ $\mathrm{ConcMgphosRBC}\mathrm{Vrbc}$ $\mathrm{ConcP6GLRBC}\mathrm{Vrbc}$ $\mathrm{ConcNadphRBC}\mathrm{Vrbc}$ $\mathrm{ConcF6PRBC}\mathrm{Vrbc}$ $\mathrm{ConcMgg16p2RBC}\mathrm{Vrbc}$ $\mathrm{ConcMgADPRBC}\mathrm{Vrbc}$ $\mathrm{ConcDhapRBC}\mathrm{Vrbc}$ $\mathrm{ConcHbB23PGRBC}\mathrm{Vrbc}$ $\mathrm{ConcGssgRBC}\mathrm{Vrbc}$ $\mathrm{ConcB13PGRBC}\mathrm{Vrbc}$ $\mathrm{ConcHbATPRBC}\mathrm{Vrbc}$ $\mathrm{ConcP3GARBC}\mathrm{Vrbc}$ $\mathrm{ConcHbRBC}\mathrm{Vrbc}$ $\mathrm{ConcHbADPRBC}\mathrm{Vrbc}$ $\mathrm{ConcBPGSPB23PGRBC}\mathrm{Vrbc}$ $\mathrm{ConcBPGSPRBC}\mathrm{Vrbc}$ $\mathrm{ConcHbB13PGRBC}\mathrm{Vrbc}$ $\mathrm{ConcGSHRBC}\mathrm{Vrbc}$ $\mathrm{ConcTKGEry4PRBC}\mathrm{Vrbc}$ $\mathrm{ConcHbmgatpRBC}\mathrm{Vrbc}$ $\mathrm{ConcPyrRBC}\mathrm{Vrbc}$ $\mathrm{ConcTKGRib5PRBC}\mathrm{Vrbc}$ $\mathrm{ConcNADPRBC}\mathrm{Vrbc}$ $\mathrm{ConcNADRBC}\mathrm{Vrbc}$ $\mathrm{ConcG6PRBC}\mathrm{Vrbc}$ $\mathrm{ConcMgRBC}\mathrm{Vrbc}$ $\mathrm{ConcMgB23PGRBC}\mathrm{Vrbc}$ $\mathrm{ConcBPGSPB13PGRBC}\mathrm{Vrbc}$ $\mathrm{ConcLacRBC}\mathrm{Vrbc}$ $\mathrm{ConcXu5PRBC}\mathrm{Vrbc}$ $\mathrm{ConcTKGRBC}\mathrm{Vrbc}$ $\mathrm{ConcGapRBC}\mathrm{Vrbc}$ $\mathrm{ConcPhosRBC}\mathrm{Vrbc}$ $\mathrm{ConcMgF16P2RBC}\mathrm{Vrbc}$ $\mathrm{ConcTkxu5pRBC}\mathrm{Vrbc}$ $\mathrm{ConcBPGSPPRBC}\mathrm{Vrbc}$ $\mathrm{ConcP2GARBC}\mathrm{Vrbc}$ $\mathrm{ConcB23PGRBC}\mathrm{Vrbc}$ $\mathrm{ConcEry4PRBC}\mathrm{Vrbc}$ $\mathrm{ConcRib5PRBC}\mathrm{Vrbc}$ $\mathrm{ConcADPRBC}\mathrm{Vrbc}$ $\mathrm{ConcSed7PRBC}\mathrm{Vrbc}$ $\mathrm{ConcMgB13PGRBC}\mathrm{Vrbc}$ $\mathrm{ConcBPGSPPP2GRBC}\mathrm{Vrbc}$ $\mathrm{ConcAMPRBC}\mathrm{Vrbc}$ $\mathrm{ConcNadhRBC}\mathrm{Vrbc}$ $\mathrm{ConcP6GRBC}\mathrm{Vrbc}$ $\mathrm{ConcTKRBC}\mathrm{Vrbc}$ $\mathrm{ConcBpgsppphosRBC}\mathrm{Vrbc}$ $\mathrm{ConcG16P2RBC}\mathrm{Vrbc}$ $\mathrm{ConcBPGSPPP3GRBC}\mathrm{Vrbc}$ $\mathrm{ConcF16P2RBC}\mathrm{Vrbc}$ $\mathrm{ConcMgatpRBC}\mathrm{Vrbc}$ $\frac{\mathrm{KigapRBCvGAPDH}}{1+\frac{10^{-\mathrm{phRBC}}}{10^{-7.5}}+\frac{10^{-10}}{10^{-\mathrm{phRBC}}}}$ $\mathrm{K13RBCvBPGSP7}\frac{1+\left(\frac{10^{-7.2}}{10^{-7.17}}\right)^4}{1+\left(\frac{10^{-\mathrm{phRBC}}}{10^{-7.17}}\right)^4}$ $\frac{\mathrm{KaRBCvMGB23PG}\mathrm{CRBCvMGB23PG}(\mathrm{KRBCvMGB23PG}+\mathrm{KhbpgRBCvMGB23PG}\mathrm{KmghbpgRBCvMGB23PG}\mathrm{hRBC})}{1+\mathrm{KhbpgRBCvMGB23PG}\mathrm{hRBC}+\mathrm{Kh2bpgRBCvMGB23PG}\mathrm{KhbpgRBCvMGB23PG}\mathrm{hRBC}\mathrm{hRBC}+\mathrm{kRBC}\mathrm{KkbpgRBCvMGB23PG}+\mathrm{kRBC}\mathrm{KhbpgRBCvMGB23PG}\mathrm{KkhbpgRBCvMGB23PG}\mathrm{hRBC}}$ $\frac{\mathrm{KaRBCvMGF16P2}\mathrm{CRBCvMGF16P2}(\mathrm{KRBCvMGF16P2}+\mathrm{KhfRBCvMGF16P2}\mathrm{KmghfRBCvMGF16P2}\mathrm{hRBC})}{1+\mathrm{KhfRBCvMGF16P2}\mathrm{hRBC}+\mathrm{Kh2fRBCvMGF16P2}\mathrm{KhfRBCvMGF16P2}\mathrm{hRBC}\mathrm{hRBC}+\mathrm{kRBC}\mathrm{KkfRBCvMGF16P2}+\mathrm{kRBC}\mathrm{KhfRBCvMGF16P2}\mathrm{KkhfRBCvMGF16P2}\mathrm{hRBC}}$ $\mathrm{K6RBCvBPGSP4}\frac{1+\left(\frac{10^{-7.2}}{10^{-7.17}}\right)^4}{1+\left(\frac{10^{-\mathrm{phRBC}}}{10^{-7.17}}\right)^4}$ $\mathrm{K1RBCvAK}(1+\mathrm{pHConversionFactor}10^{-\mathrm{phRBC}}\mathrm{KhadpRBCvAK}+\mathrm{kRBC}\mathrm{KkadpRBCvAK})$ $\mathrm{KaRBCvMGATP}\mathrm{CRBCvMGATP}\frac{\mathrm{KRBCvMGATP}+\mathrm{KhatpRBCvMGATP}\mathrm{KmghatpRBCvMGATP}\mathrm{hRBC}}{1+\frac{\frac{\mathrm{KhatpRBCvMGATP}}{\mathrm{pHConversionFactor}}}{10^{\mathrm{phRBC}}}+\mathrm{kRBC}\mathrm{KkatpRBCvMGATP}}$ $\frac{\mathrm{KaRBCvMGG16P2}\mathrm{CRBCvMGG16P2}(\mathrm{KRBCvMGG16P2}+\mathrm{KhfRBCvMGG16P2}\mathrm{KmghfRBCvMGG16P2}\mathrm{hRBC})}{1+\mathrm{KhfRBCvMGG16P2}\mathrm{hRBC}+\mathrm{Kh2fRBCvMGG16P2}\mathrm{KhfRBCvMGG16P2}\mathrm{hRBC}\mathrm{hRBC}+\mathrm{kRBC}\mathrm{KkfRBCvMGG16P2}+\mathrm{kRBC}\mathrm{KhfRBCvMGG16P2}\mathrm{KkhfRBCvMGG16P2}\mathrm{hRBC}}$ $\mathrm{K2RBCvAK}(1+\mathrm{hRBC}\mathrm{KhampRBCvAK}+\mathrm{kRBC}\mathrm{KkampRBCvAK})$ $\frac{\mathrm{KaRBCvMGB13PG}\mathrm{CRBCvMGB13PG}(\mathrm{KRBCvMGB13PG}+\mathrm{KhbpgRBCvMGB13PG}\mathrm{KmghbpgRBCvMGB13PG}\mathrm{hRBC})}{1+\mathrm{KhbpgRBCvMGB13PG}\mathrm{hRBC}+\mathrm{Kh2bpgRBCvMGB13PG}\mathrm{KhbpgRBCvMGB13PG}\mathrm{hRBC}\mathrm{hRBC}+\mathrm{kRBC}\mathrm{KkbpgRBCvMGB13PG}+\mathrm{kRBC}\mathrm{KhbpgRBCvMGB13PG}\mathrm{KkhbpgRBCvMGB13PG}\mathrm{hRBC}}$ $\frac{\mathrm{KaRBCvMGPHOS}(1+\mathrm{pHConversionFactor}10^{-7.2}\mathrm{KhphosRBCvMGPHOS}+\mathrm{kRBC}\mathrm{KkphosRBCvMGPHOS})}{1+\mathrm{hRBC}\mathrm{KhphosRBCvMGPHOS}+\mathrm{kRBC}\mathrm{KkphosRBCvMGPHOS}}$ $\frac{\mathrm{KiRBCvPHOSTRANSPORT}}{\mathrm{KeqRBCvPHOSTRANSPORT}}$ $\mathrm{KaRBCvMGADP}\mathrm{CRBCvMGADP}\frac{\mathrm{KRBCvMGADP}+\mathrm{KhadpRBCvMGADP}\mathrm{KmghadpRBCvMGADP}\mathrm{hRBC}}{1+\mathrm{KhadpRBCvMGADP}\mathrm{hRBC}+\mathrm{kRBC}\mathrm{KkadpRBCvMGADP}}$ $\mathrm{KipyrRBCvLDH}\frac{1+\frac{10^{-6.8}}{10^{-\mathrm{phRBC}}}}{1+\frac{10^{-6.8}}{10^{-7.2}}}$ $\frac{\mathrm{KcatrRBCvGAPDH}}{1+\frac{10^{-\mathrm{phRBC}}}{10^{-7.5}}+\frac{10^{-10}}{10^{-\mathrm{phRBC}}}}$ $\mathrm{KmlacRBCvLDH}\frac{1+\frac{10^{-\mathrm{phRBC}}}{10^{-6.8}}}{1+\frac{10^{-7.2}}{10^{-6.8}}}$ $\frac{1+10^{(\mathrm{phRBC}-3.73)}}{1+\frac{10^{(\mathrm{phRBC}-3.73)}}{\mathrm{RtvRBC}}}$ $\mathrm{KmnadhRBCvGAPDH}\frac{10^{-7.2}}{10^{-\mathrm{phRBC}}}$ $\mathrm{KmpyrRBCvLDH}\frac{1+\frac{10^{-6.8}}{10^{-\mathrm{phRBC}}}}{1+\frac{10^{-6.8}}{10^{-7.2}}}$ $\frac{\mathrm{KcatrRBCvHK}}{1+\frac{10^{-\mathrm{phRBC}}}{10^{-7.02}}+\frac{10^{-9.55}}{10^{-\mathrm{phRBC}}}}$ $\frac{1+\frac{2\mathrm{KahbRBC}}{\mathrm{pHConversionFactor}10^{-7.2}}+\left(\frac{\mathrm{KahbRBC}}{\mathrm{pHConversionFactor}10^{-7.2}}\right)^2}{1+\frac{2\mathrm{KahbRBC}}{\mathrm{hRBC}}+\frac{\frac{\mathrm{KahbRBC}}{\mathrm{hRBC}}\mathrm{KahbRBC}}{\mathrm{hRBC}}}$ $\frac{1+10^{(\mathrm{phRBC}-6.75)}}{\frac{1}{\mathrm{RtvRBC}}+\frac{10^{(\mathrm{phRBC}-6.75)}}{\mathrm{RtvRBC}\mathrm{RtvRBC}}}$ $\frac{\mathrm{KcatfRBCvHK}}{1+\frac{10^{-\mathrm{phRBC}}}{10^{-7.02}}+\frac{10^{-9.55}}{10^{-\mathrm{phRBC}}}}$ $\mathrm{KaRBCvHBB13PG}\mathrm{HbpHRBC}$ $\mathrm{KilacRBCvLDH}\frac{1+\frac{10^{-\mathrm{phRBC}}}{10^{-6.8}}}{1+\frac{10^{-7.2}}{10^{-6.8}}}$ $\mathrm{K4RBCvBPGSP3}\frac{1+\left(\frac{10^{-7.2}}{10^{-7.17}}\right)^4}{1+\left(\frac{10^{-\mathrm{phRBC}}}{10^{-7.17}}\right)^4}$ $\frac{\mathrm{KcatfRBCvGAPDH}}{1+\frac{10^{-\mathrm{phRBC}}}{10^{-7.5}}+\frac{10^{-10}}{10^{-\mathrm{phRBC}}}}$ $\mathrm{atpRBC}+\mathrm{adpRBC}+\mathrm{ampRBC}$ $\frac{\mathrm{KiRBCvPYRTRANSPORT}}{\mathrm{RtvRBC}}$ $\frac{\mathrm{pHConversionFactor}}{10^{\mathrm{phRBC}}}$ $\mathrm{KaRBCvHBATP}\mathrm{HbpHRBC}$ $\mathrm{KaRBCvHBADP}\mathrm{HbpHRBC}$ $\frac{\mathrm{KiRBCvLACTRANSPORT}}{\mathrm{KeqRBCvLACTRANSPORT}}$ $\mathrm{K3RBCvBPGSP2}\frac{1+\left(\frac{10^{-7.2}}{10^{-7.17}}\right)^4}{1+\left(\frac{10^{-\mathrm{phRBC}}}{10^{-7.17}}\right)^4}$ $\mathrm{KaRBCvHBBPG}\mathrm{HbpHRBC}$ $\mathrm{KinadhRBCvGAPDH}\frac{10^{-7.2}}{10^{-\mathrm{phRBC}}}$ $\mathrm{KaRBCvHBMGATP}\mathrm{HbpHRBC}$ $\mathrm{K1RBCvBPGSP1}\frac{1+\frac{10^{-6.8}}{10^{-7.2}}}{1+\frac{10^{-6.8}}{10^{-\mathrm{phRBC}}}}$ $\mathrm{adpRBC}+\mathrm{atpRBC}+\mathrm{ampRBC}+\mathrm{mgRBC}+\mathrm{mgadpRBC}+\mathrm{mgatpRBC}+\mathrm{mgb13pgRBC}+\mathrm{mgb23pgRBC}+\mathrm{mgf16p2RBC}+\mathrm{mgg16p2RBC}+\mathrm{mgphosRBC}$ $\frac{\mathrm{Kib13pgRBCvGAPDH}}{1+\frac{10^{-\mathrm{phRBC}}}{10^{-7.5}}+\frac{10^{-10}}{10^{-\mathrm{phRBC}}}}$ $\frac{\frac{\mathrm{pHConversionFactor}10^{-6.8}}{\mathrm{hRBC}}(1+\frac{\frac{\mathrm{atpRBC}}{\mathrm{Vrbc}}}{\mathrm{KtatpRBCvPK}})^4}{(1+\frac{\frac{\mathrm{f16p2RBC}}{\mathrm{Vrbc}}}{\mathrm{Krf16p2RBCvPK}}+\frac{\frac{\mathrm{g16p2RBC}}{\mathrm{Vrbc}}}{\mathrm{Krg16p2RBCvPK}})^4(1+\frac{\frac{\mathrm{pepRBC}}{\mathrm{Vrbc}}}{\mathrm{KrpepRBCvPK}}+\frac{\frac{\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KrpyrRBCvPK}})^4}$ $\mathrm{ConcLacEXT}\mathrm{vBld}$ $\mathrm{ConcPhosEXT}\mathrm{vBld}$ $\mathrm{ConcPyrEXT}\mathrm{vBld}$ $\mathrm{ConcGlcRBC}\mathrm{Vrbc}$ $\mathrm{ConcCo2RBC}\mathrm{Vrbc}$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{K1appRBCvAK}\mathrm{adpRBC}}{\mathrm{Vrbc}}\mathrm{mgadpRBC}}{\mathrm{Vrbc}}-\frac{\frac{\mathrm{K2appRBCvAK}\mathrm{ampRBC}}{\mathrm{Vrbc}}\mathrm{mgatpRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvALD}(\frac{\frac{\mathrm{f16p2RBC}}{\mathrm{Vrbc}}\mathrm{KcatfRBCvALD}}{\mathrm{Kmf16p2RBCvALD}}-\frac{\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{dhapRBC}}{\mathrm{Vrbc}}\mathrm{KcatrRBCvALD}}{\mathrm{KidhapRBCvALD}\mathrm{KmgapRBCvALD}})}{1+\frac{\frac{\mathrm{dhapRBC}}{\mathrm{Vrbc}}}{\mathrm{KidhapRBCvALD}}+\frac{\frac{\mathrm{f16p2RBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf16p2RBCvALD}}+\frac{\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{dhapRBC}}{\mathrm{Vrbc}}}{\mathrm{KidhapRBCvALD}\mathrm{KmgapRBCvALD}}+\frac{\frac{\frac{\mathrm{f16p2RBC}}{\mathrm{Vrbc}}\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{KmdhapRBCvALD}}{\mathrm{Kif16p2RBCvALD}\mathrm{KidhapRBCvALD}\mathrm{KmgapRBCvALD}}+\frac{\frac{\mathrm{b23pgRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{mgb23pgRBC}}{\mathrm{Vrbc}}}{\mathrm{Kib23pgRBCvALD}}+\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{KmdhapRBCvALD}(1+\frac{\frac{\mathrm{b23pgRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{mgb23pgRBC}}{\mathrm{Vrbc}}}{\mathrm{Kib23pgRBCvALD}})}{\mathrm{KidhapRBCvALD}\mathrm{KmgapRBCvALD}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{KRBCvATPASE}\mathrm{mgatpRBC}}{\mathrm{Vrbc}}$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{K1appRBCvBPGSP1}\mathrm{b13pgRBC}}{\mathrm{Vrbc}}\mathrm{bpgspRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{K2RBCvBPGSP1}\mathrm{bpgspb13pgRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{K3appRBCvBPGSP2}\mathrm{bpgspb13pgRBC}}{\mathrm{Vrbc}}$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{-\mathrm{K5RBCvBPGSP3}\mathrm{bpgsppp3gRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{K4appRBCvBPGSP3}\mathrm{bpgsppRBC}}{\mathrm{Vrbc}}\mathrm{p3gRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{-\mathrm{K7RBCvBPGSP4}\mathrm{bpgsppp2gRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{K6appRBCvBPGSP4}\mathrm{bpgsppRBC}}{\mathrm{Vrbc}}\mathrm{p2gRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\mathrm{K8RBCvBPGSP5}\mathrm{bpgsppp3gRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{K9RBCvBPGSP5}\mathrm{bpgspb23pgRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\mathrm{K10RBCvBPGSP6}\mathrm{bpgsppp2gRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{K11RBCvBPGSP6}\mathrm{bpgspb23pgRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{-\mathrm{K13appRBCvBPGSP7}\mathrm{b23pgRBC}}{\mathrm{Vrbc}}\mathrm{bpgspRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K12RBCvBPGSP7}\mathrm{bpgspb23pgRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{K14RBCvBPGSP8}\mathrm{bpgsppRBC}}{\mathrm{Vrbc}}\mathrm{phosRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{K15RBCvBPGSP8}\mathrm{bpgsppphosRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{K16RBCvBPGSP9}\mathrm{bpgsppphosRBC}}{\mathrm{Vrbc}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvENO}(\frac{\frac{\frac{\mathrm{KcatfRBCvENO}\mathrm{mgRBC}}{\mathrm{Vrbc}}\mathrm{p2gRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgRBCvENO}\mathrm{Kmp2gRBCvENO}}-\frac{\frac{\frac{\mathrm{KcatrRBCvENO}\mathrm{mgRBC}}{\mathrm{Vrbc}}\mathrm{pepRBC}}{\mathrm{Vrbc}}}{\mathrm{KipepRBCvENO}\mathrm{KmmgRBCvENO}})}{1+\frac{\frac{\mathrm{mgRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgRBCvENO}}+\frac{\frac{\mathrm{p2gRBC}}{\mathrm{Vrbc}}}{\mathrm{Kip2gRBCvENO}}+\frac{\frac{\frac{\mathrm{mgRBC}}{\mathrm{Vrbc}}\mathrm{p2gRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgRBCvENO}\mathrm{Kmp2gRBCvENO}}+\frac{\frac{\mathrm{pepRBC}}{\mathrm{Vrbc}}}{\mathrm{KipepRBCvENO}}+\frac{\frac{\frac{\mathrm{mgRBC}}{\mathrm{Vrbc}}\mathrm{pepRBC}}{\mathrm{Vrbc}}}{\mathrm{KipepRBCvENO}\mathrm{KmmgRBCvENO}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvG6PDH}(\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvG6PDH}\mathrm{K3RBCvG6PDH}\mathrm{K5RBCvG6PDH}\mathrm{K7RBCvG6PDH}\mathrm{K9RBCvG6PDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}-\frac{\frac{\mathrm{K2RBCvG6PDH}\mathrm{K4RBCvG6PDH}\mathrm{K6RBCvG6PDH}\mathrm{K8RBCvG6PDH}\mathrm{K10RBCvG6PDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{p6glRBC}}{\mathrm{Vrbc}})}{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{K3RBCvG6PDH}\mathrm{K5RBCvG6PDH}\mathrm{K7RBCvG6PDH}\mathrm{K9RBCvG6PDH}+\mathrm{K2RBCvG6PDH}(\mathrm{K4RBCvG6PDH}\mathrm{K6RBCvG6PDH}+\mathrm{K4RBCvG6PDH}\mathrm{K7RBCvG6PDH}+\mathrm{K5RBCvG6PDH}\mathrm{K7RBCvG6PDH})\mathrm{K9RBCvG6PDH}+\frac{\mathrm{K1RBCvG6PDH}(\mathrm{K4RBCvG6PDH}\mathrm{K6RBCvG6PDH}+\mathrm{K4RBCvG6PDH}\mathrm{K7RBCvG6PDH}+\mathrm{K5RBCvG6PDH}\mathrm{K7RBCvG6PDH})\mathrm{K9RBCvG6PDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvG6PDH}\mathrm{K3RBCvG6PDH}(\mathrm{K5RBCvG6PDH}\mathrm{K7RBCvG6PDH}+\mathrm{K5RBCvG6PDH}\mathrm{K9RBCvG6PDH}+\mathrm{K6RBCvG6PDH}\mathrm{K9RBCvG6PDH}+\mathrm{K7RBCvG6PDH}\mathrm{K9RBCvG6PDH})\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{K3RBCvG6PDH}\mathrm{K5RBCvG6PDH}\mathrm{K7RBCvG6PDH}\mathrm{K10RBCvG6PDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K2RBCvG6PDH}(\mathrm{K4RBCvG6PDH}\mathrm{K6RBCvG6PDH}+\mathrm{K5RBCvG6PDH}\mathrm{K6RBCvG6PDH}+\mathrm{K5RBCvG6PDH}\mathrm{K7RBCvG6PDH})\mathrm{K10RBCvG6PDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K2RBCvG6PDH}\mathrm{K4RBCvG6PDH}\mathrm{K6RBCvG6PDH}\mathrm{K8RBCvG6PDH}\mathrm{p6glRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{K1RBCvG6PDH}\mathrm{K4RBCvG6PDH}\mathrm{K6RBCvG6PDH}\mathrm{K8RBCvG6PDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}\mathrm{p6glRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvG6PDH}\mathrm{K3RBCvG6PDH}(\mathrm{K5RBCvG6PDH}+\mathrm{K6RBCvG6PDH})\mathrm{K8RBCvG6PDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}\mathrm{p6glRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{K3RBCvG6PDH}(\mathrm{K5RBCvG6PDH}+\mathrm{K6RBCvG6PDH})\mathrm{K8RBCvG6PDH}\mathrm{K10RBCvG6PDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{p6glRBC}}{\mathrm{Vrbc}}+\frac{\frac{(\mathrm{K2RBCvG6PDH}\mathrm{K4RBCvG6PDH}+\mathrm{K2RBCvG6PDH}\mathrm{K5RBCvG6PDH}+\mathrm{K2RBCvG6PDH}\mathrm{K6RBCvG6PDH}+\mathrm{K4RBCvG6PDH}\mathrm{K6RBCvG6PDH})\mathrm{K8RBCvG6PDH}\mathrm{K10RBCvG6PDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{p6glRBC}}{\mathrm{Vrbc}}}$ $\frac{\mathrm{TsRBC}\mathrm{Vrbc}\mathrm{VRBCvGAPDH}}{\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}}{\mathrm{KiappgapRBCvGAPDH}}(1+\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}}{\mathrm{KidgapRBCvGAPDH}})+\frac{\frac{\mathrm{b13pgRBC}}{\mathrm{Vrbc}}}{\mathrm{Kiappb13pgRBCvGAPDH}}(1+\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}}{\mathrm{KidgapRBCvGAPDH}})+\frac{\frac{\mathrm{Kmb13pgRBCvGAPDH}\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{Kiappb13pgRBCvGAPDH}\mathrm{KmappnadhRBCvGAPDH}}+\frac{\frac{\frac{\mathrm{KmgapRBCvGAPDH}\mathrm{nadRBC}}{\mathrm{Vrbc}}\mathrm{phosRBC}}{\mathrm{Vrbc}}}{\mathrm{KiappgapRBCvGAPDH}\mathrm{KmnadRBCvGAPDH}\mathrm{KiphosRBCvGAPDH}}+\frac{\frac{\frac{\mathrm{nadRBC}}{\mathrm{Vrbc}}\mathrm{gapRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvGAPDH}\mathrm{KiappgapRBCvGAPDH}}+\frac{\frac{\frac{\mathrm{phosRBC}}{\mathrm{Vrbc}}\mathrm{gapRBC}}{\mathrm{Vrbc}}}{\mathrm{KiphosRBCvGAPDH}\mathrm{KiappgapRBCvGAPDH}}(1+\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}}{\mathrm{KidgapRBCvGAPDH}})+\frac{\frac{\frac{\mathrm{nadRBC}}{\mathrm{Vrbc}}\mathrm{b13pgRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvGAPDH}\mathrm{Kiappb13pgRBCvGAPDH}}+\frac{\frac{\frac{\mathrm{Kmb13pgRBCvGAPDH}\mathrm{phosRBC}}{\mathrm{Vrbc}}\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{KiphosRBCvGAPDH}\mathrm{Kiappb13pgRBCvGAPDH}\mathrm{KmappnadhRBCvGAPDH}}+\frac{\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{KiappgapRBCvGAPDH}\mathrm{KiappnadhRBCvGAPDH}}+\frac{\frac{\frac{\mathrm{b13pgRBC}}{\mathrm{Vrbc}}\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{Kiappb13pgRBCvGAPDH}\mathrm{KmappnadhRBCvGAPDH}}+\frac{\frac{\frac{\frac{\mathrm{nadRBC}}{\mathrm{Vrbc}}\mathrm{phosRBC}}{\mathrm{Vrbc}}\mathrm{gapRBC}}{\mathrm{Vrbc}}}{\mathrm{KmnadRBCvGAPDH}\mathrm{KiphosRBCvGAPDH}\mathrm{KiappgapRBCvGAPDH}}+\frac{\frac{\frac{\frac{\mathrm{KmgapRBCvGAPDH}\mathrm{nadRBC}}{\mathrm{Vrbc}}\mathrm{phosRBC}}{\mathrm{Vrbc}}\mathrm{b13pgRBC}}{\mathrm{Vrbc}}}{\mathrm{KiappgapRBCvGAPDH}\mathrm{KmnadRBCvGAPDH}\mathrm{KiphosRBCvGAPDH}\mathrm{Kidb13pgRBCvGAPDH}}+\frac{\frac{\frac{\frac{\mathrm{phosRBC}}{\mathrm{Vrbc}}\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{KiphosRBCvGAPDH}\mathrm{KiappgapRBCvGAPDH}\mathrm{KiappnadhRBCvGAPDH}}+\frac{\frac{\frac{\frac{\mathrm{Kmb13pgRBCvGAPDH}\mathrm{phosRBC}}{\mathrm{Vrbc}}\mathrm{b13pgRBC}}{\mathrm{Vrbc}}\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{Kiappb13pgRBCvGAPDH}\mathrm{KmappnadhRBCvGAPDH}\mathrm{KiphosRBCvGAPDH}\mathrm{Kidb13pgRBCvGAPDH}}}(\frac{\frac{\frac{\frac{\mathrm{KcatfappRBCvGAPDH}\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{nadRBC}}{\mathrm{Vrbc}}\mathrm{phosRBC}}{\mathrm{Vrbc}}}{\mathrm{KmnadRBCvGAPDH}\mathrm{KiphosRBCvGAPDH}\mathrm{KiappgapRBCvGAPDH}}-\frac{\frac{\frac{\mathrm{KcatrappRBCvGAPDH}\mathrm{b13pgRBC}}{\mathrm{Vrbc}}\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{Kiappb13pgRBCvGAPDH}\mathrm{KmappnadhRBCvGAPDH}})$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvGSSGR}(\frac{\frac{\frac{-\mathrm{gshRBC}\mathrm{gshRBC}}{\mathrm{Vrbc}}}{\mathrm{Vrbc}}\mathrm{K2RBCvGSSGR}\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}\mathrm{K8RBCvGSSGR}\mathrm{K10RBCvGSSGR}\mathrm{K12RBCvGSSGR}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvGSSGR}\mathrm{K3RBCvGSSGR}\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR}\mathrm{K9RBCvGSSGR}\mathrm{K11RBCvGSSGR}\mathrm{nadphRBC}}{\mathrm{Vrbc}})}{\frac{\frac{\mathrm{gshRBC}\mathrm{gshRBC}}{\mathrm{Vrbc}}}{\mathrm{Vrbc}}\mathrm{K2RBCvGSSGR}\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}\mathrm{K8RBCvGSSGR}\mathrm{K10RBCvGSSGR}+\frac{\mathrm{gshRBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvGSSGR}\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}\mathrm{K8RBCvGSSGR}\mathrm{K11RBCvGSSGR}+\frac{\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K3RBCvGSSGR}\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR}\mathrm{K9RBCvGSSGR}\mathrm{K11RBCvGSSGR}+\mathrm{K2RBCvGSSGR}(\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}+\mathrm{K4RBCvGSSGR}\mathrm{K7RBCvGSSGR}+\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR})\mathrm{K9RBCvGSSGR}\mathrm{K11RBCvGSSGR}+\frac{\frac{\mathrm{gshRBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvGSSGR}\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}\mathrm{K8RBCvGSSGR}\mathrm{K12RBCvGSSGR}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K3RBCvGSSGR}\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR}\mathrm{K9RBCvGSSGR}\mathrm{K12RBCvGSSGR}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K2RBCvGSSGR}(\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}+\mathrm{K4RBCvGSSGR}\mathrm{K7RBCvGSSGR}+\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR})\mathrm{K9RBCvGSSGR}\mathrm{K12RBCvGSSGR}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{gshRBC}}{\mathrm{Vrbc}}\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K3RBCvGSSGR}\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR}\mathrm{K10RBCvGSSGR}\mathrm{K12RBCvGSSGR}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{gshRBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvGSSGR}(\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}+\mathrm{K4RBCvGSSGR}\mathrm{K7RBCvGSSGR}+\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR})\mathrm{K10RBCvGSSGR}\mathrm{K12RBCvGSSGR}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\frac{\mathrm{gshRBC}\mathrm{gshRBC}}{\mathrm{Vrbc}}}{\mathrm{Vrbc}}\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K3RBCvGSSGR}(\mathrm{K5RBCvGSSGR}+\mathrm{K6RBCvGSSGR})\mathrm{K8RBCvGSSGR}\mathrm{K10RBCvGSSGR}\mathrm{K12RBCvGSSGR}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{gshRBC}\mathrm{gshRBC}}{\mathrm{Vrbc}}}{\mathrm{Vrbc}}(\mathrm{K2RBCvGSSGR}\mathrm{K4RBCvGSSGR}+\mathrm{K2RBCvGSSGR}\mathrm{K5RBCvGSSGR}+\mathrm{K2RBCvGSSGR}\mathrm{K6RBCvGSSGR}+\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR})\mathrm{K8RBCvGSSGR}\mathrm{K10RBCvGSSGR}\mathrm{K12RBCvGSSGR}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{gshRBC}}{\mathrm{Vrbc}}\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvGSSGR}\mathrm{K3RBCvGSSGR}\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR}\mathrm{K10RBCvGSSGR}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{gshRBC}\mathrm{gshRBC}}{\mathrm{Vrbc}}}{\mathrm{Vrbc}}\mathrm{K1RBCvGSSGR}\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}\mathrm{K8RBCvGSSGR}\mathrm{K10RBCvGSSGR}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\frac{\mathrm{gshRBC}\mathrm{gshRBC}}{\mathrm{Vrbc}}}{\mathrm{Vrbc}}\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvGSSGR}\mathrm{K3RBCvGSSGR}(\mathrm{K5RBCvGSSGR}+\mathrm{K6RBCvGSSGR})\mathrm{K8RBCvGSSGR}\mathrm{K10RBCvGSSGR}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{gshRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvGSSGR}\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}\mathrm{K8RBCvGSSGR}\mathrm{K11RBCvGSSGR}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{gshRBC}}{\mathrm{Vrbc}}\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvGSSGR}\mathrm{K3RBCvGSSGR}(\mathrm{K5RBCvGSSGR}+\mathrm{K6RBCvGSSGR})\mathrm{K8RBCvGSSGR}\mathrm{K11RBCvGSSGR}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K1RBCvGSSGR}(\mathrm{K4RBCvGSSGR}\mathrm{K6RBCvGSSGR}+\mathrm{K4RBCvGSSGR}\mathrm{K7RBCvGSSGR}+\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR})\mathrm{K9RBCvGSSGR}\mathrm{K11RBCvGSSGR}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{gssgRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvGSSGR}\mathrm{K3RBCvGSSGR}(\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR}\mathrm{K9RBCvGSSGR}+\mathrm{K5RBCvGSSGR}\mathrm{K7RBCvGSSGR}\mathrm{K11RBCvGSSGR}+\mathrm{K5RBCvGSSGR}\mathrm{K9RBCvGSSGR}\mathrm{K11RBCvGSSGR}+\mathrm{K6RBCvGSSGR}\mathrm{K9RBCvGSSGR}\mathrm{K11RBCvGSSGR}+\mathrm{K7RBCvGSSGR}\mathrm{K9RBCvGSSGR}\mathrm{K11RBCvGSSGR})\mathrm{nadphRBC}}{\mathrm{Vrbc}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{-\mathrm{hbadpRBC}}{\mathrm{Vrbc}}\mathrm{KdRBCvHBADP}+\frac{\frac{\mathrm{KaappRBCvHBADP}\mathrm{adpRBC}}{\mathrm{Vrbc}}\mathrm{hbRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{-\mathrm{hbatpRBC}}{\mathrm{Vrbc}}\mathrm{KdRBCvHBATP}+\frac{\frac{\mathrm{KaappRBCvHBATP}\mathrm{atpRBC}}{\mathrm{Vrbc}}\mathrm{hbRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{-\mathrm{hbb13pgRBC}}{\mathrm{Vrbc}}\mathrm{KdRBCvHBB13PG}+\frac{\frac{\mathrm{KaappRBCvHBB13PG}\mathrm{b13pgRBC}}{\mathrm{Vrbc}}\mathrm{hbRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{-\mathrm{hbb23pgRBC}}{\mathrm{Vrbc}}\mathrm{KdRBCvHBBPG}+\frac{\frac{\mathrm{KaappRBCvHBBPG}\mathrm{b23pgRBC}}{\mathrm{Vrbc}}\mathrm{hbRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{-\mathrm{hbmgatpRBC}}{\mathrm{Vrbc}}\mathrm{KdRBCvHBMGATP}+\frac{\frac{\mathrm{KaappRBCvHBMGATP}\mathrm{hbRBC}}{\mathrm{Vrbc}}\mathrm{mgatpRBC}}{\mathrm{Vrbc}})$ $\frac{\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\frac{-\mathrm{KcatrappRBCvHK}\mathrm{ERBCvHK}\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{Kig6pRBCvHK}\mathrm{KmmgadpRBCvHK}}+\frac{\frac{\frac{\mathrm{KcatfappRBCvHK}\mathrm{ERBCvHK}\mathrm{glcRBC}}{\mathrm{Vrbc}}\mathrm{mgatpRBC}}{\mathrm{Vrbc}}}{\mathrm{KiglcRBCvHK}\mathrm{KmmgatpRBCvHK}})}{1+\frac{\frac{\mathrm{glcRBC}}{\mathrm{Vrbc}}}{\mathrm{KiglcRBCvHK}}+\frac{\frac{\frac{\mathrm{glcRBC}}{\mathrm{Vrbc}}\mathrm{b23pgRBC}}{\mathrm{Vrbc}}}{\mathrm{KdibpgRBCvHK}\mathrm{KiglcRBCvHK}}+\frac{\frac{\frac{\mathrm{glcRBC}}{\mathrm{Vrbc}}\mathrm{g16p2RBC}}{\mathrm{Vrbc}}}{\mathrm{Kdig16p2RBCvHK}\mathrm{KiglcRBCvHK}}+\frac{\frac{\frac{\mathrm{glcRBC}}{\mathrm{Vrbc}}\mathrm{g6pRBC}}{\mathrm{Vrbc}}}{\mathrm{Kdig6pRBCvHK}\mathrm{KiglcRBCvHK}}+\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}}{\mathrm{Kig6pRBCvHK}}+\frac{\frac{\frac{\mathrm{glcRBC}}{\mathrm{Vrbc}}\mathrm{gshRBC}}{\mathrm{Vrbc}}}{\mathrm{KdigshRBCvHK}\mathrm{KiglcRBCvHK}}+\frac{\frac{\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgadpRBCvHK}}+\frac{\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{Kig6pRBCvHK}\mathrm{KmmgadpRBCvHK}}+\frac{\frac{\mathrm{mgatpRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgatpRBCvHK}}+\frac{\frac{\frac{\mathrm{glcRBC}}{\mathrm{Vrbc}}\mathrm{mgatpRBC}}{\mathrm{Vrbc}}}{\mathrm{KiglcRBCvHK}\mathrm{KmmgatpRBCvHK}}}$ $\mathrm{TsRBC}\mathrm{vBld}(\frac{-\mathrm{KiRBCvLACTRANSPORT}\mathrm{lacEXT}}{\mathrm{vBld}}+\frac{\mathrm{KoRBCvLACTRANSPORT}\mathrm{lacRBC}}{\mathrm{Vrbc}})$ $\frac{\mathrm{TsRBC}\mathrm{Vrbc}\mathrm{VRBCvLDH}(-\left(\frac{\frac{\frac{\mathrm{KcatrRBCvLDH}\mathrm{lacRBC}}{\mathrm{Vrbc}}\mathrm{nadRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvLDH}\mathrm{KmapplacRBCvLDH}}\right)+\frac{\frac{\frac{\mathrm{KcatfRBCvLDH}\mathrm{nadhRBC}}{\mathrm{Vrbc}}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadhRBCvLDH}\mathrm{KmapppyrRBCvLDH}})}{\frac{\frac{\mathrm{nadRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvLDH}}+\frac{\frac{\frac{\mathrm{lacRBC}}{\mathrm{Vrbc}}\mathrm{nadRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvLDH}\mathrm{KmapplacRBCvLDH}}+\frac{\frac{\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadhRBCvLDH}}+\frac{\frac{\frac{\mathrm{KmnadRBCvLDH}\mathrm{lacRBC}}{\mathrm{Vrbc}}\mathrm{nadhRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvLDH}\mathrm{KinadhRBCvLDH}\mathrm{KmapplacRBCvLDH}}+\frac{\frac{\frac{\mathrm{KmnadhRBCvLDH}\mathrm{nadRBC}}{\mathrm{Vrbc}}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvLDH}\mathrm{KinadhRBCvLDH}\mathrm{KmapppyrRBCvLDH}}+\frac{\frac{\frac{\frac{\mathrm{lacRBC}}{\mathrm{Vrbc}}\mathrm{nadRBC}}{\mathrm{Vrbc}}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvLDH}\mathrm{KiapppyrRBCvLDH}\mathrm{KmapplacRBCvLDH}}+\frac{\frac{\frac{\mathrm{nadhRBC}}{\mathrm{Vrbc}}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadhRBCvLDH}\mathrm{KmapppyrRBCvLDH}}+\frac{\frac{\frac{\frac{\mathrm{lacRBC}}{\mathrm{Vrbc}}\mathrm{nadhRBC}}{\mathrm{Vrbc}}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KiapplacRBCvLDH}\mathrm{KinadhRBCvLDH}\mathrm{KmapppyrRBCvLDH}}+(1+\frac{\frac{\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KidpyrRBCvLDH}})(1+\frac{\frac{\mathrm{KmnadRBCvLDH}\mathrm{lacRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadRBCvLDH}\mathrm{KmapplacRBCvLDH}}+\frac{\frac{\mathrm{KmnadhRBCvLDH}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KinadhRBCvLDH}\mathrm{KmapppyrRBCvLDH}})}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{-\left(\frac{\frac{\frac{\mathrm{KrRBCvLDHP}\mathrm{lacRBC}}{\mathrm{Vrbc}}\mathrm{nadpRBC}}{\mathrm{Vrbc}}}{\mathrm{KmlacRBCvLDHP}}\right)+\frac{\frac{\frac{\mathrm{KfRBCvLDHP}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KmpyrRBCvLDHP}}}{1+\frac{\frac{\mathrm{lacRBC}}{\mathrm{Vrbc}}}{\mathrm{KmlacRBCvLDHP}}+\frac{\frac{\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KmpyrRBCvLDHP}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{KaappRBCvMGADP}\mathrm{adpRBC}}{\mathrm{Vrbc}}\mathrm{mgRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{KdRBCvMGADP}\mathrm{mgadpRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{KaappRBCvMGATP}\mathrm{atpRBC}}{\mathrm{Vrbc}}\mathrm{mgRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{KdRBCvMGATP}\mathrm{mgatpRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{KaappRBCvMGB13PG}\mathrm{b13pgRBC}}{\mathrm{Vrbc}}\mathrm{mgRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{KdRBCvMGB13PG}\mathrm{mgb13pgRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{KaappRBCvMGB23PG}\mathrm{b23pgRBC}}{\mathrm{Vrbc}}\mathrm{mgRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{KdRBCvMGB23PG}\mathrm{mgb23pgRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{KaappRBCvMGF16P2}\mathrm{f16p2RBC}}{\mathrm{Vrbc}}\mathrm{mgRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{KdRBCvMGF16P2}\mathrm{mgf16p2RBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{KaappRBCvMGG16P2}\mathrm{g16p2RBC}}{\mathrm{Vrbc}}\mathrm{mgRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{KdRBCvMGG16P2}\mathrm{mgg16p2RBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{-\mathrm{KdRBCvMGPHOS}\mathrm{mgphosRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{KaappRBCvMGPHOS}\mathrm{mgRBC}}{\mathrm{Vrbc}}\mathrm{phosRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{KRBCvOX}\mathrm{gshRBC}}{\mathrm{Vrbc}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{KRBCvOXNADH}\mathrm{nadhRBC}}{\mathrm{Vrbc}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvP6GDH}(\frac{\frac{\mathrm{K1RBCvP6GDH}\mathrm{K3RBCvP6GDH}\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH}\mathrm{K9RBCvP6GDH}\mathrm{K11RBCvP6GDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}\mathrm{p6gRBC}}{\mathrm{Vrbc}}-\frac{\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvP6GDH}\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}\mathrm{K8RBCvP6GDH}\mathrm{K10RBCvP6GDH}\mathrm{K12RBCvP6GDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{ru5pRBC}}{\mathrm{Vrbc}})}{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvP6GDH}\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}\mathrm{K8RBCvP6GDH}\mathrm{K11RBCvP6GDH}+\mathrm{K2RBCvP6GDH}(\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}+\mathrm{K4RBCvP6GDH}\mathrm{K7RBCvP6GDH}+\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH})\mathrm{K9RBCvP6GDH}\mathrm{K11RBCvP6GDH}+\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvP6GDH}\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}\mathrm{K8RBCvP6GDH}\mathrm{K11RBCvP6GDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K1RBCvP6GDH}(\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}+\mathrm{K4RBCvP6GDH}\mathrm{K7RBCvP6GDH}+\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH})\mathrm{K9RBCvP6GDH}\mathrm{K11RBCvP6GDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvP6GDH}\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}\mathrm{K8RBCvP6GDH}\mathrm{K12RBCvP6GDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K2RBCvP6GDH}(\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}+\mathrm{K4RBCvP6GDH}\mathrm{K7RBCvP6GDH}+\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH})\mathrm{K9RBCvP6GDH}\mathrm{K12RBCvP6GDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K3RBCvP6GDH}\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH}\mathrm{K9RBCvP6GDH}\mathrm{K11RBCvP6GDH}\mathrm{p6gRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvP6GDH}\mathrm{K3RBCvP6GDH}(\mathrm{K5RBCvP6GDH}+\mathrm{K6RBCvP6GDH})\mathrm{K8RBCvP6GDH}\mathrm{K11RBCvP6GDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}\mathrm{p6gRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{K1RBCvP6GDH}\mathrm{K3RBCvP6GDH}(\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH}\mathrm{K9RBCvP6GDH}+\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH}\mathrm{K11RBCvP6GDH}+\mathrm{K5RBCvP6GDH}\mathrm{K9RBCvP6GDH}\mathrm{K11RBCvP6GDH}+\mathrm{K6RBCvP6GDH}\mathrm{K9RBCvP6GDH}\mathrm{K11RBCvP6GDH}+\mathrm{K7RBCvP6GDH}\mathrm{K9RBCvP6GDH}\mathrm{K11RBCvP6GDH})\mathrm{nadpRBC}}{\mathrm{Vrbc}}\mathrm{p6gRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{K3RBCvP6GDH}\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH}\mathrm{K9RBCvP6GDH}\mathrm{K12RBCvP6GDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{p6gRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvP6GDH}\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}\mathrm{K8RBCvP6GDH}\mathrm{K10RBCvP6GDH}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvP6GDH}\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}\mathrm{K8RBCvP6GDH}\mathrm{K10RBCvP6GDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{K2RBCvP6GDH}(\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH}+\mathrm{K4RBCvP6GDH}\mathrm{K7RBCvP6GDH}+\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH})\mathrm{K10RBCvP6GDH}\mathrm{K12RBCvP6GDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}(\mathrm{K2RBCvP6GDH}\mathrm{K4RBCvP6GDH}+\mathrm{K2RBCvP6GDH}\mathrm{K5RBCvP6GDH}+\mathrm{K2RBCvP6GDH}\mathrm{K6RBCvP6GDH}+\mathrm{K4RBCvP6GDH}\mathrm{K6RBCvP6GDH})\mathrm{K8RBCvP6GDH}\mathrm{K10RBCvP6GDH}\mathrm{K12RBCvP6GDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{K1RBCvP6GDH}\mathrm{K3RBCvP6GDH}\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH}\mathrm{K10RBCvP6GDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}\mathrm{p6gRBC}}{\mathrm{Vrbc}}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvP6GDH}\mathrm{K3RBCvP6GDH}(\mathrm{K5RBCvP6GDH}+\mathrm{K6RBCvP6GDH})\mathrm{K8RBCvP6GDH}\mathrm{K10RBCvP6GDH}\mathrm{nadpRBC}}{\mathrm{Vrbc}}\mathrm{p6gRBC}}{\mathrm{Vrbc}}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\mathrm{K3RBCvP6GDH}\mathrm{K5RBCvP6GDH}\mathrm{K7RBCvP6GDH}\mathrm{K10RBCvP6GDH}\mathrm{K12RBCvP6GDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{p6gRBC}}{\mathrm{Vrbc}}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}+\frac{\frac{\frac{\frac{\mathrm{co2RBC}}{\mathrm{Vrbc}}\mathrm{K3RBCvP6GDH}(\mathrm{K5RBCvP6GDH}+\mathrm{K6RBCvP6GDH})\mathrm{K8RBCvP6GDH}\mathrm{K10RBCvP6GDH}\mathrm{K12RBCvP6GDH}\mathrm{nadphRBC}}{\mathrm{Vrbc}}\mathrm{p6gRBC}}{\mathrm{Vrbc}}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvPFK}(-\left(\frac{\frac{\frac{\mathrm{f16p2RBC}}{\mathrm{Vrbc}}\mathrm{KcatfRBCvPFK}\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf16p2RBCvPFK}\mathrm{KmmgadpRBCvPFK}}\right)+\frac{\frac{\frac{\mathrm{f6pRBC}}{\mathrm{Vrbc}}\mathrm{KcatfRBCvPFK}\mathrm{mgatpRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf6pRBCvPFK}\mathrm{KmmgatpRBCvPFK}})}{(1+\frac{\frac{\mathrm{f16p2RBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf16p2RBCvPFK}}+\frac{\frac{\mathrm{f6pRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf6pRBCvPFK}}+\frac{\frac{\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{KmmgadpRBCvPFK}}+\frac{\frac{\frac{\mathrm{f16p2RBC}}{\mathrm{Vrbc}}\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf16p2RBCvPFK}\mathrm{KmmgadpRBCvPFK}}+\frac{\frac{\mathrm{mgatpRBC}}{\mathrm{Vrbc}}}{\mathrm{KmmgatpRBCvPFK}}+\frac{\frac{\frac{\mathrm{f6pRBC}}{\mathrm{Vrbc}}\mathrm{mgatpRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf6pRBCvPFK}\mathrm{KmmgatpRBCvPFK}})(1+\frac{\left(\frac{\mathrm{hRBC}}{\mathrm{KaRBCvPFK}}\right)^{\mathrm{nRBCvPFK}}(1+\frac{\frac{\mathrm{atpRBC}}{\mathrm{Vrbc}}}{\mathrm{KtatpRBCvPFK}})^4(1+\frac{\frac{\mathrm{b23pgRBC}}{\mathrm{Vrbc}}}{\mathrm{Ktb23pgRBCvPFK}})^4(1+\frac{\frac{\mathrm{mgRBC}}{\mathrm{Vrbc}}}{\mathrm{KtmgRBCvPFK}})^4}{(1+\frac{\frac{\mathrm{f16p2RBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf16p2RBCvPFK}}+\frac{\frac{\mathrm{f6pRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf6pRBCvPFK}})^4(1+\frac{\frac{\mathrm{ampRBC}}{\mathrm{Vrbc}}}{\mathrm{KrampRBCvPFK}})^4(1+\frac{\frac{\mathrm{g16p2RBC}}{\mathrm{Vrbc}}}{\mathrm{Krg16p2RBCvPFK}})^4(1+\frac{\frac{\mathrm{phosRBC}}{\mathrm{Vrbc}}}{\mathrm{KrphosRBCvPFK}})^4})}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{ERBCvPGI}(-\left(\frac{\frac{\mathrm{f6pRBC}}{\mathrm{Vrbc}}\mathrm{KcatrRBCvPGI}}{\mathrm{Kmf6pRBCvPGI}}\right)+\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}\mathrm{KcatfRBCvPGI}}{\mathrm{Kmg6pRBCvPGI}})}{1+\frac{\frac{\mathrm{f6pRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmf6pRBCvPGI}}+\frac{\frac{\mathrm{g6pRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmg6pRBCvPGI}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvPGK}(\frac{\frac{\frac{\mathrm{b13pgRBC}}{\mathrm{Vrbc}}\mathrm{KcatfRBCvPGK}\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgadpRBCvPGK}\mathrm{Kmb13pgRBCvPGK}}-\frac{\frac{\frac{\mathrm{KcatrRBCvPGK}\mathrm{mgatpRBC}}{\mathrm{Vrbc}}\mathrm{p3gRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgatpRBCvPGK}\mathrm{Kmp3gRBCvPGK}})}{1+\frac{\frac{\mathrm{b13pgRBC}}{\mathrm{Vrbc}}}{\mathrm{Kib13pgRBCvPGK}}+\frac{\frac{\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgadpRBCvPGK}}+\frac{\frac{\frac{\mathrm{b13pgRBC}}{\mathrm{Vrbc}}\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgadpRBCvPGK}\mathrm{Kmb13pgRBCvPGK}}+\frac{\frac{\mathrm{mgatpRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgatpRBCvPGK}}+\frac{\frac{\mathrm{p3gRBC}}{\mathrm{Vrbc}}}{\mathrm{Kip3gRBCvPGK}}+\frac{\frac{\frac{\mathrm{mgatpRBC}}{\mathrm{Vrbc}}\mathrm{p3gRBC}}{\mathrm{Vrbc}}}{\mathrm{KimgatpRBCvPGK}\mathrm{Kmp3gRBCvPGK}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\mathrm{KhydrolRBCvPGLHYDROLYSIS}\mathrm{p6glRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{VRBCvPGLHYDROLYSIS}\mathrm{Klactonase3RBCvPGLHYDROLYSIS}\mathrm{p6glRBC}}{\mathrm{Vrbc}}}{\frac{\mathrm{Klactonase2RBCvPGLHYDROLYSIS}+\mathrm{Klactonase3RBCvPGLHYDROLYSIS}}{\mathrm{Klactonase1RBCvPGLHYDROLYSIS}}+\frac{\mathrm{p6glRBC}}{\mathrm{Vrbc}}})$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvPGM}(-\left(\frac{\frac{\mathrm{KcatrRBCvPGM}\mathrm{p2gRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmp2gRBCvPGM}}\right)+\frac{\frac{\mathrm{KcatfRBCvPGM}\mathrm{p3gRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmp3gRBCvPGM}})}{1+\frac{\frac{\mathrm{p2gRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmp2gRBCvPGM}}+\frac{\frac{\mathrm{p3gRBC}}{\mathrm{Vrbc}}}{\mathrm{Kmp3gRBCvPGM}}}$ $\mathrm{TsRBC}\mathrm{vBld}(\frac{-\mathrm{KiRBCvPHOSTRANSPORT}\mathrm{phosEXT}}{\mathrm{vBld}}+\frac{\mathrm{KoRBCvPHOSTRANSPORT}\mathrm{phosRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvPK}(\frac{\frac{\frac{\mathrm{KcatfRBCvPK}\mathrm{mgadpRBC}}{\mathrm{Vrbc}}\mathrm{pepRBC}}{\mathrm{Vrbc}}}{\mathrm{KrmgadpRBCvPK}\mathrm{KrpepRBCvPK}}-\frac{\frac{\frac{\mathrm{KcatrRBCvPK}\mathrm{mgatpRBC}}{\mathrm{Vrbc}}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KrmgatpRBCvPK}\mathrm{KrpyrRBCvPK}})}{(1+\frac{\frac{\mathrm{mgadpRBC}}{\mathrm{Vrbc}}}{\mathrm{KrmgadpRBCvPK}}+\frac{\frac{\mathrm{mgatpRBC}}{\mathrm{Vrbc}}}{\mathrm{KrmgatpRBCvPK}}+\frac{\frac{\mathrm{pepRBC}}{\mathrm{Vrbc}}}{\mathrm{KrpepRBCvPK}}+\frac{\frac{\frac{\mathrm{mgadpRBC}}{\mathrm{Vrbc}}\mathrm{pepRBC}}{\mathrm{Vrbc}}}{\mathrm{KrmgadpRBCvPK}\mathrm{KrpepRBCvPK}}+\frac{\frac{\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KrpyrRBCvPK}}+\frac{\frac{\frac{\mathrm{mgatpRBC}}{\mathrm{Vrbc}}\mathrm{pyrRBC}}{\mathrm{Vrbc}}}{\mathrm{KrmgatpRBCvPK}\mathrm{KrpyrRBCvPK}})(1+\mathrm{LRBCvPK})}$ $\mathrm{TsRBC}\mathrm{vBld}(\frac{-\mathrm{KiRBCvPYRTRANSPORT}\mathrm{pyrEXT}}{\mathrm{vBld}}+\frac{\mathrm{KoRBCvPYRTRANSPORT}\mathrm{pyrRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvR5PI}(-\left(\frac{\frac{\mathrm{K2RBCvR5PI}\mathrm{K4RBCvR5PI}\mathrm{rib5pRBC}}{\mathrm{Vrbc}}}{\mathrm{K2RBCvR5PI}+\mathrm{K3RBCvR5PI}}\right)+\frac{\frac{\mathrm{K1RBCvR5PI}\mathrm{K3RBCvR5PI}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}}{\mathrm{K2RBCvR5PI}+\mathrm{K3RBCvR5PI}})}{1+\frac{\frac{\mathrm{K1RBCvR5PI}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}}{\mathrm{K2RBCvR5PI}+\mathrm{K3RBCvR5PI}}+\frac{\frac{\mathrm{K4RBCvR5PI}\mathrm{xu5pRBC}}{\mathrm{Vrbc}}}{\mathrm{K2RBCvR5PI}+\mathrm{K3RBCvR5PI}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvRu5PE}(\frac{\frac{\mathrm{K1RBCvRu5PE}\mathrm{K3RBCvRu5PE}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}}{\mathrm{K2RBCvRu5PE}+\mathrm{K3RBCvRu5PE}}-\frac{\frac{\mathrm{K2RBCvRu5PE}\mathrm{K4RBCvRu5PE}\mathrm{xu5pRBC}}{\mathrm{Vrbc}}}{\mathrm{K2RBCvRu5PE}+\mathrm{K3RBCvRu5PE}})}{1+\frac{\frac{\mathrm{K1RBCvRu5PE}\mathrm{ru5pRBC}}{\mathrm{Vrbc}}}{\mathrm{K2RBCvRu5PE}+\mathrm{K3RBCvRu5PE}}+\frac{\frac{\mathrm{K4RBCvRu5PE}\mathrm{xu5pRBC}}{\mathrm{Vrbc}}}{\mathrm{K2RBCvRu5PE}+\mathrm{K3RBCvRu5PE}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvTA}(\frac{\frac{-\mathrm{ery4pRBC}}{\mathrm{Vrbc}}\mathrm{f6pRBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvTA}\mathrm{K4RBCvTA}\mathrm{K6RBCvTA}\mathrm{K8RBCvTA}+\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvTA}\mathrm{K3RBCvTA}\mathrm{K5RBCvTA}\mathrm{K7RBCvTA}\mathrm{sed7pRBC}}{\mathrm{Vrbc}})}{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}(\mathrm{K2RBCvTA}+\mathrm{K3RBCvTA})\mathrm{K5RBCvTA}\mathrm{K7RBCvTA}+\frac{\mathrm{ery4pRBC}}{\mathrm{Vrbc}}\mathrm{K2RBCvTA}\mathrm{K4RBCvTA}(\mathrm{K6RBCvTA}+\mathrm{K7RBCvTA})+\frac{\frac{\mathrm{f6pRBC}}{\mathrm{Vrbc}}\mathrm{gapRBC}}{\mathrm{Vrbc}}(\mathrm{K2RBCvTA}+\mathrm{K3RBCvTA})\mathrm{K5RBCvTA}\mathrm{K8RBCvTA}+\frac{\mathrm{f6pRBC}}{\mathrm{Vrbc}}(\mathrm{K2RBCvTA}+\mathrm{K3RBCvTA})\mathrm{K6RBCvTA}\mathrm{K8RBCvTA}+\frac{\frac{\mathrm{ery4pRBC}}{\mathrm{Vrbc}}\mathrm{f6pRBC}}{\mathrm{Vrbc}}\mathrm{K4RBCvTA}(\mathrm{K2RBCvTA}+\mathrm{K6RBCvTA})\mathrm{K8RBCvTA}+\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvTA}\mathrm{K5RBCvTA}(\mathrm{K3RBCvTA}+\mathrm{K7RBCvTA})\mathrm{sed7pRBC}}{\mathrm{Vrbc}}+\frac{\mathrm{K1RBCvTA}\mathrm{K3RBCvTA}(\mathrm{K6RBCvTA}+\mathrm{K7RBCvTA})\mathrm{sed7pRBC}}{\mathrm{Vrbc}}+\frac{\frac{\mathrm{ery4pRBC}}{\mathrm{Vrbc}}\mathrm{K1RBCvTA}\mathrm{K4RBCvTA}(\mathrm{K6RBCvTA}+\mathrm{K7RBCvTA})\mathrm{sed7pRBC}}{\mathrm{Vrbc}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}\frac{\mathrm{VRBCvTIM}(\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}\mathrm{KcatfRBCvTIM}}{\mathrm{KmgapRBCvTIM}}-\frac{\frac{\mathrm{dhapRBC}}{\mathrm{Vrbc}}\mathrm{KcatrRBCvTIM}}{\mathrm{KmdhapRBCvTIM}})}{1+\frac{\frac{\mathrm{gapRBC}}{\mathrm{Vrbc}}}{\mathrm{KmgapRBCvTIM}}+\frac{\frac{\mathrm{dhapRBC}}{\mathrm{Vrbc}}}{\mathrm{KmdhapRBCvTIM}}}$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{K1RBCvTK1}\mathrm{tkRBC}}{\mathrm{Vrbc}}\mathrm{xu5pRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{K2RBCvTK1}\mathrm{tkxu5pRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\mathrm{K3RBCvTK2}\mathrm{tkxu5pRBC}}{\mathrm{Vrbc}}-\frac{\frac{\mathrm{K4RBCvTK2}\mathrm{tkgRBC}}{\mathrm{Vrbc}}\mathrm{gapRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{K5RBCvTK3}\mathrm{tkgRBC}}{\mathrm{Vrbc}}\mathrm{rib5pRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{K6RBCvTK3}\mathrm{tkgrib5pRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\mathrm{K7RBCvTK4}\mathrm{tkgrib5pRBC}}{\mathrm{Vrbc}}-\frac{\frac{\mathrm{K8RBCvTK4}\mathrm{tkRBC}}{\mathrm{Vrbc}}\mathrm{sed7pRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\frac{\mathrm{K9RBCvTK5}\mathrm{tkgRBC}}{\mathrm{Vrbc}}\mathrm{ery4pRBC}}{\mathrm{Vrbc}}-\frac{\mathrm{K10RBCvTK5}\mathrm{tkgery4pRBC}}{\mathrm{Vrbc}})$ $\mathrm{TsRBC}\mathrm{Vrbc}(\frac{\mathrm{K11RBCvTK6}\mathrm{tkgery4pRBC}}{\mathrm{Vrbc}}-\frac{\frac{\mathrm{K12RBCvTK6}\mathrm{tkRBC}}{\mathrm{Vrbc}}\mathrm{f6pRBC}}{\mathrm{Vrbc}})$