$\mathrm{ADP}\mathrm{AMP}\mathrm{ATP}\mathrm{k1}\mathrm{k2}\mapsto \mathrm{k1}\mathrm{ADP}^2-\mathrm{AMP}\mathrm{ATP}\mathrm{k2}$ $\mathrm{Vfmax}\mathrm{Keq}\mathrm{S1}\mathrm{Ks1}\mathrm{S2}\mathrm{Ks2}\mathrm{P1}\mathrm{Kp1}\mathrm{P2}\mathrm{Kp2}\mathrm{I1}\mathrm{Ki1}\mathrm{I2}\mathrm{Ki2}\mapsto \frac{\mathrm{Vfmax}\mathrm{S1}\mathrm{S2}(1-\frac{\mathrm{P1}\mathrm{P2}}{\mathrm{Keq}\mathrm{S1}\mathrm{S2}})}{\mathrm{Ks1}\mathrm{Ks2}(1+\frac{\mathrm{S1}}{\mathrm{Ks1}}+\frac{\mathrm{P1}}{\mathrm{Kp1}})(1+\frac{\mathrm{S2}}{\mathrm{Ks2}}+\frac{\mathrm{P2}}{\mathrm{Kp2}}+\frac{\mathrm{I1}}{\mathrm{Ki1}}+\frac{\mathrm{I2}}{\mathrm{Ki2}})}$ $\mathrm{Vfmax}\mathrm{Keq}S\mathrm{Ks}P\mathrm{Kp}\mapsto \frac{\mathrm{Vfmax}S(1-\frac{P}{\mathrm{Keq}S})}{\mathrm{Ks}(1+\frac{S}{\mathrm{Ks}}+\frac{P}{\mathrm{Kp}})}$ $kS\mapsto kS$ $\mathrm{Vfmax}\mathrm{Keq}\mathrm{S1}\mathrm{Ks1}\mathrm{S2}\mathrm{Ks2}\mathrm{P1}\mathrm{Kp1}\mathrm{P2}\mathrm{Kp2}\mapsto \frac{\mathrm{Vfmax}\mathrm{S1}\mathrm{S2}(1-\frac{\mathrm{P1}\mathrm{P2}}{\mathrm{Keq}\mathrm{S1}\mathrm{S2}})}{\mathrm{Ks1}\mathrm{Ks2}(1+\frac{\mathrm{S1}}{\mathrm{Ks1}}+\frac{\mathrm{P1}}{\mathrm{Kp1}})(1+\frac{\mathrm{S2}}{\mathrm{Ks2}}+\frac{\mathrm{P2}}{\mathrm{Kp2}})}$ $\mathrm{Vfmax}S\mathrm{Ks}\mapsto \frac{\mathrm{Vfmax}S}{\mathrm{Ks}(1+\frac{S}{\mathrm{Ks}})}$ $\mathrm{k1}S\mathrm{k2}P\mapsto \mathrm{k1}S-\mathrm{k2}P$ $\mathrm{vAK}(\mathrm{ADP\_c}, \mathrm{AMP\_c}, \mathrm{ATP\_c}, \mathrm{AK\_c\_k1}, \mathrm{AK\_c\_k2})$ $\mathrm{vAK}(\mathrm{ADP\_g}, \mathrm{AMP\_g}, \mathrm{ATP\_g}, \mathrm{AK\_g\_k1}, \mathrm{AK\_g\_k2})$ $\frac{\mathrm{ALD\_g\_Vmax}\mathrm{Fru16BP\_g}(1-\frac{\mathrm{GA3P\_g}\mathrm{DHAP\_g}}{\mathrm{Fru16BP\_g}\mathrm{ALD\_g\_Keq}})}{\mathrm{ALD\_g\_KmFru16BP}(1+\frac{\mathrm{ATP\_g}}{\mathrm{ALD\_g\_KiATP}}+\frac{\mathrm{ADP\_g}}{\mathrm{ALD\_g\_KiADP}}+\frac{\mathrm{AMP\_g}}{\mathrm{ALD\_g\_KiAMP}})(1+\frac{\mathrm{GA3P\_g}}{\mathrm{ALD\_g\_KmGA3P}}+\frac{\mathrm{DHAP\_g}}{\mathrm{ALD\_g\_KmDHAP}}+\frac{\mathrm{Fru16BP\_g}}{\mathrm{ALD\_g\_KmFru16BP}(1+\frac{\mathrm{ATP\_g}}{\mathrm{ALD\_g\_KiATP}}+\frac{\mathrm{ADP\_g}}{\mathrm{ALD\_g\_KiADP}}+\frac{\mathrm{AMP\_g}}{\mathrm{ALD\_g\_KiAMP}})}+\frac{\mathrm{GA3P\_g}\mathrm{DHAP\_g}}{\mathrm{ALD\_g\_KmGA3P}\mathrm{ALD\_g\_KmDHAP}}+\frac{\mathrm{Fru16BP\_g}\mathrm{GA3P\_g}}{\mathrm{ALD\_g\_KmFru16BP}\mathrm{ALD\_g\_KiGA3P}(1+\frac{\mathrm{ATP\_g}}{\mathrm{ALD\_g\_KiATP}}+\frac{\mathrm{ADP\_g}}{\mathrm{ALD\_g\_KiADP}}+\frac{\mathrm{AMP\_g}}{\mathrm{ALD\_g\_KiAMP}})})}$ $\frac{\mathrm{ATPu\_c\_k}\mathrm{ATP\_c}}{\mathrm{ADP\_c}}$ $\mathrm{v1sub1prod}(\mathrm{ENO\_c\_Vmax}, \mathrm{ENO\_c\_Keq}, \mathrm{\_2PGA\_c}, \mathrm{ENO\_c\_Km2PGA}, \mathrm{PEP\_c}, \mathrm{ENO\_c\_KmPEP})$ $\mathrm{v2sub2prod}(\mathrm{G3PDH\_g\_Vmax}, \mathrm{G3PDH\_g\_Keq}, \mathrm{DHAP\_g}, \mathrm{G3PDH\_g\_KmDHAP}, \mathrm{NADH\_g}, \mathrm{G3PDH\_g\_KmNADH}, \mathrm{Gly3P\_g}, \mathrm{G3PDH\_g\_KmGly3P}, \mathrm{NAD\_g}, \mathrm{G3PDH\_g\_KmNAD})$ $\mathrm{v2sub2prod}(\mathrm{G6PDH\_c\_Vmax}, \mathrm{G6PDH\_c\_Keq}, \mathrm{Glc6P\_c}, \mathrm{G6PDH\_c\_KmGlc6P}, \mathrm{NADP\_c}, \mathrm{G6PDH\_c\_KmNADP}, \mathrm{\_6PGL\_c}, \mathrm{G6PDH\_c\_Km6PGL}, \mathrm{NADPH\_c}, \mathrm{G6PDH\_c\_KmNADPH})$ $\mathrm{v2sub2prod}(\mathrm{G6PDH\_g\_Vmax}, \mathrm{G6PDH\_g\_Keq}, \mathrm{Glc6P\_g}, \mathrm{G6PDH\_g\_KmGlc6P}, \mathrm{NADP\_g}, \mathrm{G6PDH\_g\_KmNADP}, \mathrm{\_6PGL\_g}, \mathrm{G6PDH\_g\_Km6PGL}, \mathrm{NADPH\_g}, \mathrm{G6PDH\_g\_KmNADPH})$ $\mathrm{v1sub1prod}(\mathrm{G6PP\_c\_Vmax}, \mathrm{G6PP\_c\_Keq}, \mathrm{Glc6P\_c}, \mathrm{G6PP\_c\_KmGlc6P}, \mathrm{Glc\_c}, \mathrm{G6PP\_c\_KmGlc})$ $\mathrm{v2sub2prod}(\mathrm{GAPDH\_g\_Vmax}, \mathrm{GAPDH\_g\_Keq}, \mathrm{GA3P\_g}, \mathrm{GAPDH\_g\_KmGA3P}, \mathrm{NAD\_g}, \mathrm{GAPDH\_g\_KmNAD}, \mathrm{\_13BPGA\_g}, \mathrm{GAPDH\_g\_Km13BPGA}, \mathrm{NADH\_g}, \mathrm{GAPDH\_g\_KmNADH})$ $\mathrm{Gly3P\_g}\mathrm{GDA\_g\_k}\mathrm{DHAP\_c}-\mathrm{Gly3P\_c}\mathrm{GDA\_g\_k}\mathrm{DHAP\_g}$ $\mathrm{v2sub2prod}(\mathrm{GK\_g\_Vmax}, \mathrm{GK\_g\_Keq}, \mathrm{Gly3P\_g}, \mathrm{GK\_g\_KmGly3P}, \mathrm{ADP\_g}, \mathrm{GK\_g\_KmADP}, \mathrm{Gly\_e}, \mathrm{GK\_g\_KmGly}, \mathrm{ATP\_g}, \mathrm{GK\_g\_KmATP})$ $\mathrm{v1sub}(\mathrm{GPO\_c\_Vmax}, \mathrm{Gly3P\_c}, \mathrm{GPO\_c\_KmGly3P})$ $\frac{\mathrm{GlcT\_c\_Vmax}(\mathrm{Glc\_e}-\mathrm{Glc\_c})}{\mathrm{GlcT\_c\_KmGlc}+\mathrm{Glc\_e}+\mathrm{Glc\_c}+\frac{\mathrm{GlcT\_c\_alpha}\mathrm{Glc\_e}\mathrm{Glc\_c}}{\mathrm{GlcT\_c\_KmGlc}}}$ $\mathrm{mass\_action\_rev}(\mathrm{GlcT\_g\_k1}, \mathrm{Glc\_c}, \mathrm{GlcT\_g\_k2}, \mathrm{Glc\_g})$ $\mathrm{v2sub2prod}(\mathrm{HXK\_c\_Vmax}, \mathrm{HXK\_c\_Keq}, \mathrm{Glc\_c}, \mathrm{HXK\_c\_KmGlc}, \mathrm{ATP\_c}, \mathrm{HXK\_c\_KmATP}, \mathrm{Glc6P\_c}, \mathrm{HXK\_c\_KmGlc6P}, \mathrm{ADP\_c}, \mathrm{HXK\_c\_KmADP})$ $\mathrm{v2sub2prod}(\mathrm{HXK\_g\_Vmax}, \mathrm{HXK\_g\_Keq}, \mathrm{Glc\_g}, \mathrm{HXK\_g\_KmGlc}, \mathrm{ATP\_g}, \mathrm{HXK\_g\_KmATP}, \mathrm{Glc6P\_g}, \mathrm{HXK\_g\_KmGlc6P}, \mathrm{ADP\_g}, \mathrm{HXK\_g\_KmADP})$ $\mathrm{mass\_action\_irrev}(\mathrm{NADPHu\_c\_k}, \mathrm{NADPH\_c})$ $\mathrm{mass\_action\_irrev}(\mathrm{NADPHu\_g\_k}, \mathrm{NADPH\_g})$ $\frac{\mathrm{PFK\_g\_Vmax}\mathrm{PFK\_g\_Ki1}\mathrm{Fru6P\_g}\mathrm{ATP\_g}(1-\frac{\mathrm{Fru16BP\_g}\mathrm{ADP\_g}}{\mathrm{PFK\_g\_Keq}\mathrm{Fru6P\_g}\mathrm{ATP\_g}})}{\mathrm{PFK\_g\_KmFru6P}\mathrm{PFK\_g\_KmATP}(\mathrm{Fru16BP\_g}+\mathrm{PFK\_g\_Ki1})(\frac{\mathrm{PFK\_g\_KsATP}}{\mathrm{PFK\_g\_KmATP}}+\frac{\mathrm{Fru6P\_g}}{\mathrm{PFK\_g\_KmFru6P}}+\frac{\mathrm{ATP\_g}}{\mathrm{PFK\_g\_KmATP}}+\frac{\mathrm{ADP\_g}}{\mathrm{PFK\_g\_KmADP}}+\frac{\mathrm{Fru16BP\_g}\mathrm{ADP\_g}}{\mathrm{PFK\_g\_KmADP}\mathrm{PFK\_g\_Ki2}}+\frac{\mathrm{Fru6P\_g}\mathrm{ATP\_g}}{\mathrm{PFK\_g\_KmFru6P}\mathrm{PFK\_g\_KmATP}})}$ $\mathrm{v1sub1prod}(\mathrm{PGAM\_c\_Vmax}, \mathrm{PGAM\_c\_Keq}, \mathrm{\_3PGA\_c}, \mathrm{PGAM\_c\_Km3PGA}, \mathrm{\_2PGA\_c}, \mathrm{PGAM\_c\_Km2PGA})$ $\frac{\mathrm{PGI\_g\_Vmax}\mathrm{Glc6P\_g}(1-\frac{\mathrm{Fru6P\_g}}{\mathrm{PGI\_g\_Keq}\mathrm{Glc6P\_g}})}{\mathrm{PGI\_g\_KmGlc6P}(1+\frac{\mathrm{Glc6P\_g}}{\mathrm{PGI\_g\_KmGlc6P}}+\frac{\mathrm{Fru6P\_g}}{\mathrm{PGI\_g\_KmFru6P}}+\frac{\mathrm{\_6PG\_g}}{\mathrm{PGI\_g\_Ki6PG}})}$ $\mathrm{v2sub2prod}(\mathrm{PGK\_g\_Vmax}, \mathrm{PGK\_g\_Keq}, \mathrm{\_13BPGA\_g}, \mathrm{PGK\_g\_Km13BPGA}, \mathrm{ADP\_g}, \mathrm{PGK\_g\_KmADP}, \mathrm{\_3PGA\_g}, \mathrm{PGK\_g\_Km3PGA}, \mathrm{ATP\_g}, \mathrm{PGK\_g\_KmATP})$ $\mathrm{PGL\_c\_k}\mathrm{cytosol}(\mathrm{\_6PGL\_c}-\frac{\mathrm{\_6PG\_c}}{\mathrm{PGL\_c\_Keq}})+\mathrm{v1sub1prod}(\mathrm{PGL\_c\_Vmax}, \mathrm{PGL\_c\_Keq}, \mathrm{\_6PGL\_c}, \mathrm{PGL\_c\_Km6PGL}, \mathrm{\_6PG\_c}, \mathrm{PGL\_c\_Km6PG})$ $\mathrm{glycosome}\mathrm{PGL\_g\_k}(\mathrm{\_6PGL\_g}-\frac{\mathrm{\_6PG\_g}}{\mathrm{PGL\_g\_Keq}})+\mathrm{v1sub1prod}(\mathrm{PGL\_g\_Vmax}, \mathrm{PGL\_g\_Keq}, \mathrm{\_6PGL\_g}, \mathrm{PGL\_g\_Km6PGL}, \mathrm{\_6PG\_g}, \mathrm{PGL\_g\_Km6PG})$ $\mathrm{v1sub1prod}(\mathrm{PPI\_c\_Vmax}, \mathrm{PPI\_c\_Keq}, \mathrm{Rul5P\_c}, \mathrm{PPI\_c\_KmRul5P}, \mathrm{Rib5P\_c}, \mathrm{PPI\_c\_KmRib5P})$ $\mathrm{v1sub1prod}(\mathrm{PPI\_g\_Vmax}, \mathrm{PPI\_g\_Keq}, \mathrm{Rul5P\_g}, \mathrm{PPI\_g\_KmRul5P}, \mathrm{Rib5P\_g}, \mathrm{PPI\_g\_KmRib5P})$ $\frac{\mathrm{PYK\_c\_Vmax}\mathrm{ADP\_c}(1-\frac{\mathrm{Pyr\_c}\mathrm{ATP\_c}}{\mathrm{PYK\_c\_Keq}\mathrm{PEP\_c}\mathrm{ADP\_c}})\left(\frac{\mathrm{PEP\_c}}{\mathrm{PYK\_c\_KmPEP}(1+\frac{\mathrm{ADP\_c}}{\mathrm{PYK\_c\_KiADP}}+\frac{\mathrm{ATP\_c}}{\mathrm{PYK\_c\_KiATP}})}\right)^{\mathrm{PYK\_c\_n}}}{\mathrm{PYK\_c\_KmADP}(1+\left(\frac{\mathrm{PEP\_c}}{\mathrm{PYK\_c\_KmPEP}(1+\frac{\mathrm{ADP\_c}}{\mathrm{PYK\_c\_KiADP}}+\frac{\mathrm{ATP\_c}}{\mathrm{PYK\_c\_KiATP}})}\right)^{\mathrm{PYK\_c\_n}}+\frac{\mathrm{Pyr\_c}}{\mathrm{PYK\_c\_KmPyr}})(1+\frac{\mathrm{ADP\_c}}{\mathrm{PYK\_c\_KmADP}}+\frac{\mathrm{ATP\_c}}{\mathrm{PYK\_c\_KmATP}})}$ $\mathrm{v1sub}(\mathrm{PyrT\_c\_Vmax}, \mathrm{Pyr\_c}, \mathrm{PyrT\_c\_KmPyr})$ $\mathrm{v2sub2prod}(\mathrm{RK\_g\_Vmax}, \mathrm{RK\_g\_Keq}, \mathrm{Rib5P\_g}, \mathrm{RK\_g\_KmRib5P}, \mathrm{ADP\_g}, \mathrm{RK\_g\_KmADP}, \mathrm{Rib\_g}, \mathrm{RK\_g\_KmRib}, \mathrm{ATP\_g}, \mathrm{RK\_g\_KmATP})$ $\mathrm{mass\_action\_irrev}(\mathrm{TOX\_c\_k}, \mathrm{TSH2\_c})$ $\mathrm{v1sub1prod}(\mathrm{TPI\_g\_Vmax}, \mathrm{TPI\_g\_Keq}, \mathrm{DHAP\_g}, \mathrm{TPI\_g\_KmDHAP}, \mathrm{GA3P\_g}, \mathrm{TPI\_g\_KmGA3P})$ $\mathrm{v2sub2prod}(\mathrm{TR\_c\_Vmax}, \mathrm{TR\_c\_Keq}, \mathrm{TS2\_c}, \mathrm{TR\_c\_KmTS2}, \mathrm{NADPH\_c}, \mathrm{TR\_c\_KmNADPH}, \mathrm{TSH2\_c}, \mathrm{TR\_c\_KmTSH2}, \mathrm{NADP\_c}, \mathrm{TR\_c\_KmNADP})$ $\mathrm{mass\_action\_rev}(\mathrm{\_3PGAT\_g\_k}, \mathrm{\_3PGA\_g}, \mathrm{\_3PGAT\_g\_k}, \mathrm{\_3PGA\_c})$ $\mathrm{v2sub2prod}(\mathrm{\_6PGDH\_c\_Vmax}, \mathrm{\_6PGDH\_c\_Keq}, \mathrm{\_6PG\_c}, \mathrm{\_6PGDH\_c\_Km6PG}, \mathrm{NADP\_c}, \mathrm{\_6PGDH\_c\_KmNADP}, \mathrm{Rul5P\_c}, \mathrm{\_6PGDH\_c\_KmRul5P}, \mathrm{NADPH\_c}, \mathrm{\_6PGDH\_c\_KmNADPH})$ $\mathrm{v2sub2prod}(\mathrm{\_6PGDH\_g\_Vmax}, \mathrm{\_6PGDH\_g\_Keq}, \mathrm{\_6PG\_g}, \mathrm{\_6PGDH\_g\_Km6PG}, \mathrm{NADP\_g}, \mathrm{\_6PGDH\_g\_KmNADP}, \mathrm{Rul5P\_g}, \mathrm{\_6PGDH\_g\_KmRul5P}, \mathrm{NADPH\_g}, \mathrm{\_6PGDH\_g\_KmNADPH})$